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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL306197
Molecular formula	C25H32N2O
IUPAC name	N-[3-(2-methoxyphenyl)propyl]-N-propyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
Molecular weight	376.544
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	6.0
Synonyms	N-[3-(2-Methoxyphenyl)propyl]-N-propyl-6,7,8,9-tetrahydro-3H-benz[e]indol-8-amine [3-(2-Methoxy-phenyl)-propyl]-propyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine BDBM50035358
Inchi Key	AAYJEWYLPYARLE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H32N2O/c1-3-16-27(17-6-8-20-7-4-5-9-25(20)28-2)21-12-10-19-11-13-24-22(14-15-26-24)23(19)18-21/h4-5,7,9,11,13-15,21,26H,3,6,8,10,12,16-18H2,1-2H3
PubChem CID	11740280
ChEMBL	CHEMBL306197
IUPHAR	N/A
BindingDB	50035358
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
623	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
622	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
624	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
626	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
625	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446

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