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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	7-OH-DPAT
Molecular formula	C16H25NO
IUPAC name	7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol
Molecular weight	247.382
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	4.1
Synonyms	Lopac0_000616 PDSP1_001643 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol 7-OH-DPAT,(-) BPBio1_001143 D03PYX DP-7-AT NCGC00015494-04 [3H]-7-OH-DPAT (+)-7-hydroxy-2-aminopropylaminotetralin 3-(dipropylamino)tetralin-6-ol 7-Hydroxy-2-N,N-dipropylaminotetralin AC1L1AZK CCG-204705 I14-4633 NCGC00024742-02 (+/-)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin 7-(Dipropylamino)-5,6,7,8-tetrahydro-2-naphthalenol BDBM50020222 CHEMBL285755 LS-94989 PDSP2_001627 2-Naphthalenol, 7-(dipropylamino)-5,6,7,8-tetrahydro- 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol (DP-7-ADTN) 7-Ohdpat BRD-A18795974-001-01-2 D0XQ8N GTPL3296 NCGC00015494-05 [3H]7-OH-DPAT (+)7-OH-DPAT 7-Hydroxy-DPAT hydrobromide AC1Q7AGR CHEBI:111176 L000014 NCGC00024742-03 (R,S) 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol 7-OH-DPAT,(+) Biomol-NT_000011 CTK5E0721 N,N-Di-n-propyl-7-hydroxy-2-aminotetralin SCHEMBL623950 (+)-7-(Dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol hydrobromide 2-Naphthalenol,7-(dipropylamino)-5,6,7,8-tetrahydro- 7-hydroxy-2-(dipropylamino)tetralin BRD-A18795974-004-02-4 D0Z4QZ GTPL950 NCGC00015494-06 (+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol 7-Hydroxy-N,N-di-n-propyl-2-aminotetralin AKOS015913437 [ Show all ]
Inchi Key	BLYMJBIZMIGWFK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3
PubChem CID	1219
ChEMBL	CHEMBL285755
IUPHAR	3296, 950
BindingDB	50020222
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
27127	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
27128	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
555591	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
27126	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
27123	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
27130	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
27124	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
27125	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446
27129	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467
27132	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
27131	Histamine H2 receptor	P47747	HRH2	Cavia porcellus (Guinea pig)	359

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