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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL339960
Molecular formula	C23H26Cl2N4O
IUPAC name	N-[4-[4-(2,4-dichlorophenyl)piperazin-1-yl]butyl]-1H-indole-2-carboxamide
Molecular weight	445.388
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	5.3
Synonyms	N-[4-[4-(2,4-dichlorophenyl)piperazin-1-yl]butyl]indole-2-carboxamide BDBM50131925 L022291 1H-Indole-2-carboxylic acid {4-[4-(2,4-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide N-(4-(4-(2,4-dichlorophenyl)piperazin-1-yl)butyl)-1H-indole-2-carboxamide
Inchi Key	CYNHGJORJGHXEX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H26Cl2N4O/c24-18-7-8-22(19(25)16-18)29-13-11-28(12-14-29)10-4-3-9-26-23(30)21-15-17-5-1-2-6-20(17)27-21/h1-2,5-8,15-16,27H,3-4,9-14H2,(H,26,30)
PubChem CID	10411237
ChEMBL	CHEMBL339960
IUPHAR	N/A
BindingDB	50131925
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
53695	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
53694	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
53692	Alpha-2A adrenergic receptor	P22909	Adra2a	Rattus norvegicus (Rat)	450
53697	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
53698	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
523100	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
53693	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446
53696	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400

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