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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL561511
Molecular formula	C29H36N4O2
IUPAC name	[4-[2-[(5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)-propylamino]ethyl]piperazin-1-yl]-quinolin-3-ylmethanone
Molecular weight	472.633
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.5
Synonyms	(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-quinolin-3-ylmethanone D-331 (4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-quinolin-3-yl-methanone SCHEMBL2700583 BDBM50294849 CORRNILCUDTMSS-UHFFFAOYSA-N [ Show all ]
Inchi Key	CORRNILCUDTMSS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H36N4O2/c1-2-12-32(25-10-11-26-22(20-25)7-5-9-28(26)34)16-13-31-14-17-33(18-15-31)29(35)24-19-23-6-3-4-8-27(23)30-21-24/h3-9,19,21,25,34H,2,10-18,20H2,1H3
PubChem CID	45268070
ChEMBL	CHEMBL561511
IUPHAR	N/A
BindingDB	50294849
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
46947	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
46948	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446

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