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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	(+)-sulpiride
Molecular formula	C15H23N3O4S
IUPAC name	N-[[(2R)-1-ethylpyrrolidin-2-yl]methyl]-2-methoxy-5-sulfamoylbenzamide
Molecular weight	341.426
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	0.6
Synonyms	Eglonyl (TN) Hoechst Brand of Sulpiride Levosulpiride [INN] NCGC00015966-01 Pontiride S 8010 (R)-(+)-5-aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide Sulpiride (JP15/USAN/INN) Sulpor BDBM81775 vertigo neogama D03QGM FT-0630504 KS-00000XKE Lopac-S-7771 Neuraxpharm (TN) R-(+)-sulpiride SCHEMBL15475031 (R)-sulpiride Sulpiride-high,(-) Allphar Brand of Sulpiride Tocris-0894 Bosnyl (TN) ZINC20229 Desitin Brand of Sulpiride Dogmatyl (TN) Hennig Brand of Sulpiride Levopraid Meresa (TN) PDSP2_001633 Rosemont Brand of Sulpiride Sulperide 4109R0VM5R Sulpiryd (TN) Arminol Uriach Brand of Sulpiride Ekilid Hormosan Brand of Sulpiride Levosulpiride-d3 NCGC00015966-02 Psicofarma Brand of Sulpiride Sanofi Synthelabo Brand of Sulpiride (R)-(+)-sulpiride Sulpiride, (+)- AC1LD7D1 Sulpride Benzamide, 5-(aminosulfonyl)-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy-, (R)- Vertigo-Meresa Deponerton Fumouzer Brand of Sulpiride Lebopride Lopac-S-8010 PDSP1_000619 R. D. 1403 Spyfarma Brand of Sulpiride (RS)-( inverted exclamation markA)-Sulpiride Sulpiride-low,(-) Almirall Brand of Sulpiride UNII-4109R0VM5R Centrum Brand of Sulpiride Digton Dolorgiet Brand of Sulpiride Hexal Brand of Sulpiride Levosulpirida N-[[(2R)-1-ethylpyrrolidin-2-yl]methyl]-2-methoxy-5-sulfamoylbenzamide Pharmacia Brand of Sulpiride RV-12309 (inverted question mark)-Sulpiride Sulpirid (TN) Sulpivert B6492 Vertigo Meresa CHEMBL196677 Erempharma Brand of Sulpiride Krewel Brand of Sulpiride Levosulpiridum NCGC00024852-01 R(+)-SULPIRIDE Sanofi-Synthelabo Brand of Sulpiride (R)-(-)-N-[(1-Ethyl-2-pyrrolidinyl)methyl]-5-sulfamoyl-o-anisamide Sulpiride-d ACM124020275 Tepavil Benzamide, 5-(aminosulfonyl)-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-methoxy- vertigo-neogama Desisulpid GTPL960 Levobren Magnetic resonance imaging sulpiride PDSP2_000617 Ratiopharm (TN) Sulp 23756-79-8 Sulpiride-R Areu Brand of Sulpiride UNII-7MNE9M8287 component BGRJTUBHPOOWDU-LLVKDONJSA-N CHEBI:64122 Dogmatil (TN) [ Show all ]
Inchi Key	BGRJTUBHPOOWDU-LLVKDONJSA-N
Inchi ID	InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m1/s1
PubChem CID	643497
ChEMBL	CHEMBL196677
IUPHAR	960
BindingDB	81775
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
23330	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
23334	D(1A) dopamine receptor	Q61616	Drd1	Mus musculus (Mouse)	446
23332	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
553362	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
555567	D(2) dopamine receptor	P61168	Drd2	Mus musculus (Mouse)	444
553363	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
553364	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446
553361	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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