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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(1A) dopamine receptor
Species	Sus scrofa (Pig)
Gene	DRD1
Synonym	Dopamine D1 receptor
Disease	N/A for non-human GPCRs
Length	446
Amino acid sequence	MRTLNTSTMDGTGLVVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNVTSLGKTTHNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPAECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTSTNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIASPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
UniProt	P50130
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5067
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL407818
Molecular formula	C18H20N4O
IUPAC name	4-[4-(pyrazolo[1,5-a]pyridin-3-ylmethyl)piperazin-1-yl]phenol
Molecular weight	308.385
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.1
Synonyms	BDBM50373489
Inchi Key	GDEQPGACTRNZFK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H20N4O/c23-17-6-4-16(5-7-17)21-11-9-20(10-12-21)14-15-13-19-22-8-2-1-3-18(15)22/h1-8,13,23H,9-12,14H2
PubChem CID	24824066
ChEMBL	CHEMBL407818
IUPHAR	N/A
BindingDB	50373489
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	9900.0 nM	PMID18307287	BindingDB,ChEMBL

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