You can:
Name | D(1A) dopamine receptor |
---|---|
Species | Sus scrofa (Pig) |
Gene | DRD1 |
Synonym | Dopamine D1 receptor |
Disease | N/A for non-human GPCRs |
Length | 446 |
Amino acid sequence | MRTLNTSTMDGTGLVVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNVTSLGKTTHNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPAECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTSTNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIASPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT |
UniProt | P50130 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL5067 |
IUPHAR | N/A |
DrugBank | N/A |
Name | CHEMBL3318831 |
---|---|
Molecular formula | C46H48Cl2F2N2O6 |
IUPAC name | bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] butanedioate |
Molecular weight | 833.795 |
Hydrogen bond acceptor | 10 |
Hydrogen bond donor | 0 |
XlogP | 8.4 |
Synonyms | BDBM50053376 |
Inchi Key | FCLHHKLNBKMBPS-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C46H48Cl2F2N2O6/c47-37-13-9-35(10-14-37)45(23-29-51(30-24-45)27-1-3-41(53)33-5-17-39(49)18-6-33)57-43(55)21-22-44(56)58-46(36-11-15-38(48)16-12-36)25-31-52(32-26-46)28-2-4-42(54)34-7-19-40(50)20-8-34/h5-20H,1-4,21-32H2 |
PubChem CID | 118709159 |
ChEMBL | CHEMBL3318831 |
IUPHAR | N/A |
BindingDB | 50053376 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Ki | 130.0 nM | PMID25047579 | BindingDB,ChEMBL |
zhanglabzhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417