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Name | D(1A) dopamine receptor |
---|---|
Species | Sus scrofa (Pig) |
Gene | DRD1 |
Synonym | Dopamine D1 receptor |
Disease | N/A for non-human GPCRs |
Length | 446 |
Amino acid sequence | MRTLNTSTMDGTGLVVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNVTSLGKTTHNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPAECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTSTNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIASPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT |
UniProt | P50130 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL5067 |
IUPHAR | N/A |
DrugBank | N/A |
Name | CHEMBL562591 |
---|---|
Molecular formula | C18H19Cl2N5 |
IUPAC name | 3-[[4-(3,4-dichlorophenyl)piperazin-1-yl]methyl]-7-methylimidazo[1,2-c]pyrimidine |
Molecular weight | 376.285 |
Hydrogen bond acceptor | 4 |
Hydrogen bond donor | 0 |
XlogP | 4.2 |
Synonyms | N/A |
Inchi Key | DAUUMAXRGYSFJL-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C18H19Cl2N5/c1-13-8-18-21-10-15(25(18)12-22-13)11-23-4-6-24(7-5-23)14-2-3-16(19)17(20)9-14/h2-3,8-10,12H,4-7,11H2,1H3 |
PubChem CID | 45272555 |
ChEMBL | CHEMBL562591 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Activity | 0.0 % | PMID19481941 | ChEMBL |
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