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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL562591
Molecular formula	C18H19Cl2N5
IUPAC name	3-[[4-(3,4-dichlorophenyl)piperazin-1-yl]methyl]-7-methylimidazo[1,2-c]pyrimidine
Molecular weight	376.285
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.2
Synonyms	N/A
Inchi Key	DAUUMAXRGYSFJL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H19Cl2N5/c1-13-8-18-21-10-15(25(18)12-22-13)11-23-4-6-24(7-5-23)14-2-3-16(19)17(20)9-14/h2-3,8-10,12H,4-7,11H2,1H3
PubChem CID	45272555
ChEMBL	CHEMBL562591
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
443899	D(1A) dopamine receptor	P50130	DRD1	Sus scrofa (Pig)	446
443901	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
443900	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
523140	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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