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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1257811
Molecular formula	C23H28ClNO2
IUPAC name	4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(2,5-dimethylphenyl)butan-1-one
Molecular weight	385.932
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	3.9
Synonyms	4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(2,5-dimethylphenyl)butan-1-one BDBM50328447
Inchi Key	DRDXZCGSMVSSLQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H28ClNO2/c1-17-5-6-18(2)21(16-17)22(26)4-3-13-25-14-11-23(27,12-15-25)19-7-9-20(24)10-8-19/h5-10,16,27H,3-4,11-15H2,1-2H3
PubChem CID	49782603
ChEMBL	CHEMBL1257811
IUPHAR	N/A
BindingDB	50328447
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
66875	5-hydroxytryptamine receptor 2A	P50129	HTR2A	Sus scrofa (Pig)	470
66874	D(1A) dopamine receptor	P50130	DRD1	Sus scrofa (Pig)	446
66872	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
66873	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
523511	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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