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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL378680
Molecular formula	C18H18Cl2N4
IUPAC name	2-[[4-(3,4-dichlorophenyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridine
Molecular weight	361.27
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	4.5
Synonyms	896238-14-5 KB-272909 2-[4-(3,4-dichlorophenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyridine AKOS003971352 ZINC14195406 BDBM50189848 imidazo[1,2-a]pyridine,2-[[4-(3,4-dichlorophenyl)-1-piperazinyl]methyl]- [ Show all ]
Inchi Key	CVPLGARGNFQLNC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H18Cl2N4/c19-16-5-4-15(11-17(16)20)23-9-7-22(8-10-23)12-14-13-24-6-2-1-3-18(24)21-14/h1-6,11,13H,7-10,12H2
PubChem CID	11516033
ChEMBL	CHEMBL378680
IUPHAR	N/A
BindingDB	50189848
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
51698	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
51699	5-hydroxytryptamine receptor 2A	P50129	HTR2A	Sus scrofa (Pig)	470
51696	D(1A) dopamine receptor	P50130	DRD1	Sus scrofa (Pig)	446
51697	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
51701	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
51700	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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