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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL198993
Molecular formula	C21H27FN4O2
IUPAC name	6-fluoro-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]pyridine-3-carboxamide
Molecular weight	386.471
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	2.9
Synonyms	6-Fluoro-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-nicotinamide BDBM50172861 6-fluoro-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)nicotinamide
Inchi Key	DOVTZHSQYCZIIX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H27FN4O2/c1-28-19-7-3-2-6-18(19)26-14-12-25(13-15-26)11-5-4-10-23-21(27)17-8-9-20(22)24-16-17/h2-3,6-9,16H,4-5,10-15H2,1H3,(H,23,27)
PubChem CID	44403214
ChEMBL	CHEMBL198993
IUPHAR	N/A
BindingDB	50172861
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
65389	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
65392	D(1A) dopamine receptor	P50130	DRD1	Sus scrofa (Pig)	446
65390	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
65388	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
65391	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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