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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL197195
Molecular formula	C20H23Cl2FN4O
IUPAC name	N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-6-fluoropyridine-2-carboxamide
Molecular weight	425.329
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.5
Synonyms	6-Fluoro-pyridine-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide BDBM50172864
Inchi Key	HZYGVALVFFNNGE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H23Cl2FN4O/c21-15-5-3-7-17(19(15)22)27-13-11-26(12-14-27)10-2-1-9-24-20(28)16-6-4-8-18(23)25-16/h3-8H,1-2,9-14H2,(H,24,28)
PubChem CID	44403224
ChEMBL	CHEMBL197195
IUPHAR	N/A
BindingDB	50172864
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
128136	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
128139	D(1A) dopamine receptor	P50130	DRD1	Sus scrofa (Pig)	446
128137	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
128138	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
128135	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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