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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(1A) dopamine receptor
Species	Sus scrofa (Pig)
Gene	DRD1
Synonym	Dopamine D1 receptor
Disease	N/A for non-human GPCRs
Length	446
Amino acid sequence	MRTLNTSTMDGTGLVVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNVTSLGKTTHNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPAECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTSTNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIASPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
UniProt	P50130
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5067
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL212160
Molecular formula	C22H24N6O
IUPAC name	2-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-5-pyrazol-1-ylimidazo[1,2-a]pyridine
Molecular weight	388.475
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.5
Synonyms	BDBM50189844 2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]-5-(pyrazol-1-yl)imidazo[1,2-a]pyridine
Inchi Key	BZHJMSJFFNOURP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H24N6O/c1-29-20-7-3-2-6-19(20)26-14-12-25(13-15-26)16-18-17-27-21(24-18)8-4-9-22(27)28-11-5-10-23-28/h2-11,17H,12-16H2,1H3
PubChem CID	11689612
ChEMBL	CHEMBL212160
IUPHAR	N/A
BindingDB	50189844
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	27000.0 nM	PMID16789750	BindingDB,ChEMBL

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