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Ligand

NameLY-193525
Molecular formulaC22H29N3O
IUPAC name(6aR,9R,10aR)-N-cyclohexyl-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
Molecular weight351.494
Hydrogen bond acceptor2
Hydrogen bond donor2
XlogP3.5
SynonymsLY 193525
BDBM84933
6-Methyl-N-cyclohexylergoline-8A?A(2)-carboxamide
CHEMBL422708
Inchi KeyKOFNTRSDRGFTGZ-XFQXTVEOSA-N
Inchi IDInChI=1S/C22H29N3O/c1-25-13-15(22(26)24-16-6-3-2-4-7-16)10-18-17-8-5-9-19-21(17)14(12-23-19)11-20(18)25/h5,8-9,12,15-16,18,20,23H,2-4,6-7,10-11,13H2,1H3,(H,24,26)/t15-,18-,20-/m1/s1
PubChem CID44373084
ChEMBLN/A
IUPHARN/A
BindingDB84933
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 7
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
1739815-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
1739845-hydroxytryptamine receptor 2AP50128HTR2AMacaca mulatta (Rhesus macaque)471
1739855-hydroxytryptamine receptor 2AP50129HTR2ASus scrofa (Pig)470
5561605-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
1739825-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
1739835-hydroxytryptamine receptor 2BP30994Htr2bRattus norvegicus (Rat)479
1739805-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458

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