You can:
| Name | 5-hydroxytryptamine receptor 2B |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Htr2b |
| Synonym | stomach fundus serotonin receptor serotonin receptor 2B 5-HT-2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 5-HT2F [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 479 |
| Amino acid sequence | MASSYKMSEQSTISEHILQKTCDHLILTDRSGLKAESAAEEMKQTAENQGNTVHWAALLIFAVIIPTIGGNILVILAVSLEKRLQYATNYFLMSLAVADLLVGLFVMPIALLTIMFEATWPLPLALCPAWLFLDVLFSTASIMHLCAISLDRYIAIKKPIQANQCNSRTTAFVKITVVWLISIGIAIPVPIKGIEADVVNAHNITCELTKDRFGSFMLFGSLAAFFAPLTIMIVTYFLTIHALRKKAYLVRNRPPQRLTRWTVSTVLQREDSSFSSPEKMVMLDGSHKDKILPNSTDETLMRRMSSAGKKPAQTISNEQRASKVLGIVFLFFLLMWCPFFITNVTLALCDSCNQTTLKTLLQIFVWVGYVSSGVNPLIYTLFNKTFREAFGRYITCNYQATKSVKVLRKCSSTLYFGNSMVENSKFFTKHGIRNGINPAMYQSPVRLRSSTIQSSSIILLNTFLTENDGDKVEDQVSYI |
| UniProt | P30994 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL323 |
| IUPHAR | 7 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 3206 |  CHEMBL318956 | C21H22N2O2 | 334.419 | 3 / 1 | 3.5 | Yes |
| 4617 |  CHEMBL95112 | C23H27FN2O2S | 414.539 | 6 / 0 | 3.4 | Yes |
| 5315 |  CHEMBL2260621 | C17H17NO3S | 315.387 | 5 / 1 | 3.5 | Yes |
| 7071 |  CHEMBL109673 | C22H24FNO2S | 385.497 | 5 / 0 | 4.1 | Yes |
| 8139 |  CHEMBL329133 | C23H28N2O2 | 364.489 | 3 / 2 | 4.8 | Yes |
| 8199 |  BW-723C86 | C16H18N2OS | 286.393 | 3 / 2 | 3.0 | Yes |
| 11060 |  tryptamine | C10H12N2 | 160.22 | 1 / 2 | 1.6 | Yes |
| 12745 |  CHEMBL175272 | C10H15NO2 | 181.235 | 3 / 2 | 1.4 | Yes |
| 13653 |  8-OH-Dpat | C16H25NO | 247.382 | 2 / 1 | 4.1 | Yes |
| 14119 |  CHEMBL2260619 | C17H17NO2S | 299.388 | 4 / 0 | 4.6 | Yes |
| 15456 |  CHEMBL87717 | C23H24FNO2 | 365.448 | 4 / 0 | 4.0 | Yes |
| 16260 |  CHEMBL111189 | C24H29FN2O2S | 428.566 | 6 / 0 | 3.8 | Yes |
| 16788 |  Pipamperone | C21H30FN3O2 | 375.488 | 5 / 1 | 2.0 | Yes |
| 16884 |  Glemanserin | C20H25NO | 295.426 | 2 / 1 | 3.8 | Yes |
| 18322 |  CHEMBL357870 | C16H14N4O | 278.315 | 2 / 2 | 1.8 | Yes |
| 21708 |  79440-52-1 | C12H19NO2S | 241.349 | 4 / 1 | 2.2 | Yes |
| 23159 |  CHEMBL134519 | C11H16INO2 | 321.158 | 3 / 1 | 2.5 | Yes |
| 23171 |  1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine | C11H16INO2 | 321.158 | 3 / 1 | 2.5 | Yes |
| 24249 |  2-Methoxyethoxymethyl chloride | C4H9ClO2 | 124.564 | 2 / 0 | 0.6 | Yes |
| 553392 |  Rauwolscine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 26572 |  Yohimbine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 27593 |  2-phenethyl-1H-benzo[d]imidazole | C15H14N2 | 222.291 | 1 / 1 | 3.5 | Yes |
| 27901 |  CHEMBL96641 | C24H24N2O2 | 372.468 | 3 / 2 | 4.7 | Yes |
| 27927 |  CHEMBL422471 | C12H18N2 | 190.29 | 2 / 0 | 2.1 | Yes |
| 28201 |  CHEMBL92990 | C26H32N2O2 | 404.554 | 3 / 2 | 6.0 | No |
| 33980 |  CHEMBL319298 | C20H22N2O2 | 322.408 | 3 / 2 | 3.4 | Yes |
| 34861 |  CHEMBL444269 | C21H24N2O2 | 336.435 | 4 / 0 | 3.1 | Yes |
| 37755 |  CHEMBL148385 | C18H18N4O | 306.369 | 2 / 1 | 2.0 | Yes |
| 40601 |  CHEMBL328748 | C21H23IN2O2 | 462.331 | 3 / 2 | 4.4 | Yes |
| 40965 |  16502-01-5 | C11H12N2 | 172.231 | 1 / 2 | 1.5 | Yes |
| 41326 |  5-Bromotryptamine | C10H11BrN2 | 239.116 | 1 / 2 | 1.3 | Yes |
| 42040 |  CHEMBL93129 | C22H25ClN2O2 | 384.904 | 3 / 1 | 4.9 | Yes |
| 43159 |  64022-27-1 | C8H11ClN4 | 198.654 | 4 / 1 | 0.5 | Yes |
| 558650 |  CHEMBL2260626 | C16H14N2O | 250.301 | 2 / 2 | 3.9 | Yes |
| 48148 |  CHEMBL343455 | C18H18N4O | 306.369 | 2 / 1 | 2.1 | Yes |
| 48824 |  CHEMBL422923 | C14H14N4O2 | 270.292 | 3 / 2 | 1.7 | Yes |
| 49318 |  BRN 0628732 | C21H24N2O3 | 352.434 | 4 / 2 | 3.4 | Yes |
| 52602 |  CHEMBL87943 | C24H26FNO2 | 379.475 | 4 / 0 | 4.4 | Yes |
| 53770 |  1-(1H-indol-2-yl)-2-phenylethanamine | C16H16N2 | 236.318 | 1 / 2 | 2.9 | Yes |
| 56086 |  CHEMBL96427 | C22H26N2O2 | 350.462 | 3 / 2 | 4.1 | Yes |
| 56683 |  cisapride | C23H29ClFN3O4 | 465.95 | 7 / 2 | 3.4 | Yes |
| 57075 |  2,4,6-TRIMETHOXYAMPHETAMINE | C12H19NO3 | 225.288 | 4 / 1 | 1.6 | Yes |
| 59083 |  CHEMBL329479 | C22H20N2 | 312.416 | 1 / 2 | 4.7 | Yes |
| 60102 |  2,3-Dimethoxyamphetamine | C11H17NO2 | 195.262 | 3 / 1 | 1.5 | Yes |
| 62198 |  spiperone | C23H26FN3O2 | 395.478 | 5 / 1 | 3.0 | Yes |
| 63401 |  CHEMBL111509 | C24H27FN2O2 | 394.49 | 5 / 0 | 3.1 | Yes |
| 64040 |  N,N-DIMETHYLTRYPTAMINE | C12H16N2 | 188.274 | 1 / 1 | 2.5 | Yes |
| 66699 |  2,4-Dimethoxyamphetamine | C11H17NO2 | 195.262 | 3 / 1 | 1.8 | Yes |
| 68202 |  CHEMBL94940 | C21H24N2 | 304.437 | 1 / 2 | 4.6 | Yes |
| 69990 |  CHEMBL96165 | C18H16Cl2N2 | 331.24 | 1 / 2 | 4.7 | Yes |
| 71466 |  CHEMBL2260620 | C15H13NOS | 255.335 | 3 / 1 | 3.7 | Yes |
| 72639 |  tyramine | C8H11NO | 137.182 | 2 / 2 | 1.1 | Yes |
| 73080 |  CHEMBL96752 | C20H21BrN2O2 | 401.304 | 3 / 2 | 4.1 | Yes |
| 77149 |  CHEMBL160907 | C25H28F2N2O2 | 426.508 | 6 / 0 | 3.8 | Yes |
| 78614 |  CHEMBL93292 | C21H24N2O2 | 336.435 | 3 / 2 | 3.8 | Yes |
| 78860 |  Pizotifen | C19H21NS | 295.444 | 2 / 0 | 3.8 | Yes |
| 79965 |  CHEMBL319105 | C21H23N3O4 | 381.432 | 5 / 2 | 3.6 | Yes |
| 80083 |  CHEMBL94613 | C20H19F3N2 | 344.381 | 4 / 2 | 4.7 | Yes |
| 81684 |  CHEMBL357517 | C17H20N4O2 | 312.373 | 6 / 0 | 1.3 | Yes |
| 83133 |  CHEMBL161241 | C13H17N | 187.286 | 1 / 0 | 2.6 | Yes |
| 83857 |  Ketanserin | C22H22FN3O3 | 395.434 | 5 / 1 | 2.6 | Yes |
| 84282 |  CHEMBL96483 | C23H22N2O2 | 358.441 | 4 / 3 | 2.0 | Yes |
| 84533 |  CHEMBL274589 | C18H23NO2 | 285.387 | 3 / 1 | 3.9 | Yes |
| 85311 |  6711-46-2 | C10H16N2 | 164.252 | 2 / 1 | 1.5 | Yes |
| 88404 |  5-Chlorotryptamine | C10H11ClN2 | 194.662 | 1 / 2 | 1.2 | Yes |
| 88705 |  27692-91-7 | C12H20N2 | 192.306 | 2 / 0 | 2.8 | Yes |
| 89740 |  Brolamfetamine | C11H16BrNO2 | 274.158 | 3 / 1 | 2.6 | Yes |
| 93436 |  CHEMBL96559 | C21H24N2O2 | 336.435 | 3 / 2 | 3.8 | Yes |
| 93549 |  CHEMBL1202891 | C23H25ClN2 | 364.917 | 2 / 3 | N/A | N/A |
| 95237 |  CHEMBL109528 | C20H24N2O2S | 356.484 | 5 / 0 | 3.2 | Yes |
| 96570 |  CHEMBL343666 | C16H13N3OS | 295.36 | 3 / 1 | 2.7 | Yes |
| 96681 |  CHEMBL140663 | C13H17N | 187.286 | 0 / 0 | 4.3 | Yes |
| 97237 |  CHEMBL336042 | C14H19N | 201.313 | 0 / 0 | 4.0 | Yes |
| 99816 |  CHEMBL109548 | C22H22FNO2 | 351.421 | 4 / 0 | 3.4 | Yes |
| 101206 |  LY86057 | C20H26N2O3 | 342.439 | 4 / 2 | 2.4 | Yes |
| 101540 |  UNII-UGT5535REQ | C17H18ClNO | 287.787 | 2 / 1 | 4.0 | Yes |
| 101746 |  4-(2-Aminopropyl)-2-methoxyphenol | C10H15NO2 | 181.235 | 3 / 2 | 0.6 | Yes |
| 102407 |  CHEMBL175205 | C10H15NO2 | 181.235 | 3 / 2 | 1.4 | Yes |
| 104566 |  CHEMBL421002 | C20H21IN2O2 | 448.304 | 3 / 2 | 4.1 | Yes |
| 105381 |  CHEMBL2260613 | C15H14N2O | 238.29 | 2 / 2 | 2.7 | Yes |
| 105897 |  CHEMBL159689 | C13H19N | 189.302 | 1 / 0 | 2.9 | Yes |
| 106628 |  CHEMBL319005 | C19H20N2O | 292.382 | 2 / 2 | 3.4 | Yes |
| 108344 |  CHEMBL159929 | C22H24FNO3 | 369.436 | 5 / 0 | 3.5 | Yes |
| 110354 |  CHEMBL96813 | C20H22N2O2 | 322.408 | 3 / 3 | 3.5 | Yes |
| 114372 |  CHEMBL94655 | C20H20F2N2O2 | 358.389 | 5 / 2 | 3.6 | Yes |
| 115666 |  CHEMBL110847 | C21H26N2O2S | 370.511 | 5 / 0 | 3.7 | Yes |
| 116860 |  CHEMBL2260617 | C15H13NO2 | 239.274 | 3 / 1 | 2.9 | Yes |
| 121952 |  CHEMBL92755 | C22H21BrN2 | 393.328 | 2 / 2 | 5.5 | No |
| 122306 |  CHEMBL96782 | C22H26N2O2 | 350.462 | 3 / 2 | 4.1 | Yes |
| 126072 |  Pirenperone | C23H24FN3O2 | 393.462 | 5 / 0 | 2.6 | Yes |
| 132819 |  SB 200646 hydrochloride | C15H15ClN4O | 302.762 | 2 / 3 | N/A | N/A |
| 133453 |  5-(2-Aminopropyl)-2-methoxyphenol | C10H15NO2 | 181.235 | 3 / 2 | 0.6 | Yes |
| 133474 |  CHEMBL121744 | C24H27N3O2 | 389.499 | 4 / 1 | 3.7 | Yes |
| 136105 |  CHEMBL96827 | C20H21ClN2O2 | 356.85 | 3 / 2 | 4.0 | Yes |
| 138634 |  CHEMBL163180 | C19H23N3OS | 341.473 | 5 / 0 | 3.0 | Yes |
| 138927 |  CHEMBL2260612 | C17H18N2O2 | 282.343 | 3 / 1 | 3.7 | Yes |
| 140844 |  CHEMBL160019 | C21H26N2O3 | 354.45 | 5 / 0 | 3.1 | Yes |
| 141638 |  CHEMBL84888 | C18H18N4O | 306.369 | 2 / 1 | 2.1 | Yes |
| 142934 |  CHEMBL143937 | C18H21N3O2 | 311.385 | 5 / 0 | 1.9 | Yes |
| 143218 |  CHEMBL161751 | C12H17N | 175.275 | 1 / 1 | 2.5 | Yes |
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