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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL143937
Molecular formula	C18H21N3O2
IUPAC name	6-[(4-pyridin-2-ylpiperazin-1-yl)methyl]-6,7-dihydro-5H-1-benzofuran-4-one
Molecular weight	311.385
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	1.9
Synonyms	6,7-Dihydro-6-[[4-(2-pyridinyl)piperazino]methyl]benzofuran-4(5H)-one BDBM50409061
Inchi Key	IVSGQJPRVWTHND-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H21N3O2/c22-16-11-14(12-17-15(16)4-10-23-17)13-20-6-8-21(9-7-20)18-3-1-2-5-19-18/h1-5,10,14H,6-9,11-13H2
PubChem CID	10804995
ChEMBL	CHEMBL143937
IUPHAR	N/A
BindingDB	50409061
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
142935	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
142934	5-hydroxytryptamine receptor 2B	P30994	Htr2b	Rattus norvegicus (Rat)	479
142932	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
142933	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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