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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL357517
Molecular formula	C17H20N4O2
IUPAC name	6-[(4-pyrimidin-2-ylpiperazin-1-yl)methyl]-6,7-dihydro-5H-1-benzofuran-4-one
Molecular weight	312.373
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	1.3
Synonyms	6,7-Dihydro-6-[[4-(2-pyrimidinyl)piperazino]methyl]benzofuran-4(5H)-one BDBM50409064
Inchi Key	FLXRQZHNCDCQLM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H20N4O2/c22-15-10-13(11-16-14(15)2-9-23-16)12-20-5-7-21(8-6-20)17-18-3-1-4-19-17/h1-4,9,13H,5-8,10-12H2
PubChem CID	10710246
ChEMBL	CHEMBL357517
IUPHAR	N/A
BindingDB	50409064
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
81682	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
81684	5-hydroxytryptamine receptor 2B	P30994	Htr2b	Rattus norvegicus (Rat)	479
81681	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
81683	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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