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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL111189
Molecular formula	C24H29FN2O2S
IUPAC name	5-[2-[4-[4-(4-fluorophenyl)-4-oxobutyl]piperazin-1-yl]ethyl]-6,7-dihydro-5H-1-benzothiophen-4-one
Molecular weight	428.566
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	3.8
Synonyms	BDBM50409495 QF-0602B
Inchi Key	AWPTVVFLXLCOBI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H29FN2O2S/c25-20-6-3-18(4-7-20)22(28)2-1-11-26-13-15-27(16-14-26)12-9-19-5-8-23-21(24(19)29)10-17-30-23/h3-4,6-7,10,17,19H,1-2,5,8-9,11-16H2
PubChem CID	10693836
ChEMBL	CHEMBL111189
IUPHAR	N/A
BindingDB	50409495
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
16261	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
16260	5-hydroxytryptamine receptor 2B	P30994	Htr2b	Rattus norvegicus (Rat)	479
16262	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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