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Name | cisapride |
---|---|
Molecular formula | C23H29ClFN3O4 |
IUPAC name | 4-amino-5-chloro-N-[1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-yl]-2-methoxybenzamide |
Molecular weight | 465.95 |
Hydrogen bond acceptor | 7 |
Hydrogen bond donor | 2 |
XlogP | 3.4 |
Synonyms | D00274 DTXSID3022825 HMS3370F16 104860-73-3 MCULE-7144129340 [ Show all ] |
Inchi Key | DCSUBABJRXZOMT-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C23H29ClFN3O4/c1-30-21-13-19(26)18(24)12-17(21)23(29)27-20-8-10-28(14-22(20)31-2)9-3-11-32-16-6-4-15(25)5-7-16/h4-7,12-13,20,22H,3,8-11,14,26H2,1-2H3,(H,27,29) |
PubChem CID | 2769 |
ChEMBL | CHEMBL1729 |
IUPHAR | 240 |
BindingDB | 50005836 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
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GLASS ID | Name | UniProt | Gene | Species | Length |
---|---|---|---|---|---|
56675 | 5-hydroxytryptamine receptor 1A | P08908 | HTR1A | Homo sapiens (Human) | 422 |
56691 | 5-hydroxytryptamine receptor 1A | P19327 | Htr1a | Rattus norvegicus (Rat) | 422 |
56673 | 5-hydroxytryptamine receptor 2A | P28223 | HTR2A | Homo sapiens (Human) | 471 |
56681 | 5-hydroxytryptamine receptor 2A | P14842 | Htr2a | Rattus norvegicus (Rat) | 471 |
56699 | 5-hydroxytryptamine receptor 2A | Q75Z89 | HTR2A | Bos taurus (Bovine) | 470 |
56683 | 5-hydroxytryptamine receptor 2B | P30994 | Htr2b | Rattus norvegicus (Rat) | 479 |
56690 | 5-hydroxytryptamine receptor 2B | P41595 | HTR2B | Homo sapiens (Human) | 481 |
56682 | 5-hydroxytryptamine receptor 2C | P28335 | HTR2C | Homo sapiens (Human) | 458 |
56671 | 5-hydroxytryptamine receptor 4 | O70528 | HTR4 | Cavia porcellus (Guinea pig) | 388 |
56677 | 5-hydroxytryptamine receptor 4 | Q13639 | HTR4 | Homo sapiens (Human) | 388 |
56686 | 5-hydroxytryptamine receptor 4 | Q62758 | Htr4 | Rattus norvegicus (Rat) | 406 |
553518 | 5-hydroxytryptamine receptor 4 | P97288 | Htr4 | Mus musculus (Mouse) | 388 |
56689 | 5-hydroxytryptamine receptor 6 | Q9R1C8 | Htr6 | Mus musculus (Mouse) | 440 |
553517 | 5-hydroxytryptamine receptor 7 | P32304 | Htr7 | Mus musculus (Mouse) | 448 |
56697 | Alpha-1A adrenergic receptor | P43140 | Adra1a | Rattus norvegicus (Rat) | 466 |
56700 | Alpha-1A adrenergic receptor | P18130 | ADRA1A | Bos taurus (Bovine) | 466 |
56693 | Alpha-1B adrenergic receptor | P15823 | Adra1b | Rattus norvegicus (Rat) | 515 |
56684 | Alpha-1D adrenergic receptor | P25100 | ADRA1D | Homo sapiens (Human) | 572 |
56674 | Alpha-2A adrenergic receptor | P08913 | ADRA2A | Homo sapiens (Human) | 450 |
56679 | Alpha-2A adrenergic receptor | P22909 | Adra2a | Rattus norvegicus (Rat) | 450 |
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