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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL160019
Molecular formula	C21H26N2O3
IUPAC name	5-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-6,7-dihydro-5H-1-benzofuran-4-one
Molecular weight	354.45
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.1
Synonyms	5-[2-[4-(2-Methoxyphenyl)piperazino]ethyl]-6,7-dihydrobenzofuran-4(5H)-one BDBM50409489
Inchi Key	ISMVUGWKBNSWMT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H26N2O3/c1-25-20-5-3-2-4-18(20)23-13-11-22(12-14-23)10-8-16-6-7-19-17(21(16)24)9-15-26-19/h2-5,9,15-16H,6-8,10-14H2,1H3
PubChem CID	11760018
ChEMBL	CHEMBL160019
IUPHAR	N/A
BindingDB	50409489
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
140842	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
140844	5-hydroxytryptamine receptor 2B	P30994	Htr2b	Rattus norvegicus (Rat)	479
140843	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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