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You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
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Ligand

Name	Pizotifen
Molecular formula	C19H21NS
IUPAC name	1-methyl-4-(6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-2-ylidene)piperidine
Molecular weight	295.444
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	3.8
Synonyms	MLS006011927 P2344 4-(9,10-Dihydro-4H-benzo(4,5)cyclohepta(1,2-b)thien-4-ylidene)-1-methylpiperidine Pizotifen (INN) Pizotifenum [INN-Latin] AC1Q7FY1 Sandomigram BC203862 SCHEMBL44122 BRN 0753534 CS-1870 DSSTox_RID_77051 H903 NCGC00163169-02 1-methyl-4-{6-thiatricyclo[8.4.0.0?,?]tetradeca-1(14),3(7),4,10,12-pentaen-2-ylidene}piperidine Piperidine, 4-(9,10-dihydro-4H-benzo(4,5)cyclohepta(1,2-b)thien-4-ylidene)-1-methyl- 4-OXO-9,10-DIHYDRO-4H-BENZO(4,5) CYCLOHEPTO(1,2,B) Pizotifene AB00514749 Pizotyline maleate (Salt/Mix) API0003882 Sandomygran Biomol-NT_000102 Tox21_112024 CAS-15574-96-6 D06XZR FIADGNVRKBPQEU-UHFFFAOYSA-N L000722 NSC_27400 4-(1-Methyl-4-piperidylidene)-9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophene Pizotifan 4-[9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene]-1-methylpiperidine Pizotifeno [INN-Spanish] AC-11996 Pizotylline BC 105 SBI-0206788.P001 BRD-K75958195-037-03-7 W-108016 DSSTox_CID_3490 FT-0655575 MCULE-5738749931 MolPort-002-654-036 PDSP1_001602 4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine Pizotifen [INN] PIZOTYLINE AKOS005612964 Sandomigran BCP14794 SMR004703517 C-18523 CTK8G2451 DTXSID6023490 HY-B0115 NCGC00163169-03 1-methyl-4-{6-thiatricyclo[8.4.0.0^{3,7}]tetradeca-1(14),3(7),4,10,12-pentaen-2-ylidene}piperidine Piperidine, 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methyl- 4-OXO-9,10-DIHYDRO-4H-BENZO(4,5) CYCLOHEPTO(1,2,B) THIOPHENE Pizotifene [INN-French] AB00514749_11 Pizotyline [USAN] AS-13328 Sanmigran BPBio1_001391 Tox21_112024_1 CAS_15574-96-6 FT-0082645 Litec MFCD00864192 Oprea1_684518 4-(9,10-dihydro-1-thiabenzo[f]azulen-4-ylidene)-1-methylpiperidine 574P966 Pizotifenum AC1L1D4Y Polomigran BC-105 SC-46107 BRD-K75958195-037-04-5 ZINC1968 CHEMBL294951 DSSTox_GSID_23490 GTPL93 NCGC00163169-01 0BY8440V3N PDSP2_001586 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine Pizotifen, >=98% (HPLC) AB0013346 Pizotyline (USAN) AN-920 Sandomigran (TN) BDBM82088 STK801341 C19H21NS D05523 EINECS 239-632-9 KS-000017QX NCGC00163169-05 15574-96-6 Piperidine,4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methyl- 4-Oxo-9,10-dihydro-4H-benzo(4,5) cyclohepto(1,2,b)thiophene Pizotifeno AB00514749_12 Pizotyline; 4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine BBL009911 Sanomigran BRD-K75958195-001-01-7 UNII-0BY8440V3N CHEBI:50212 DB06153 FT-0637249 LS-115012 [ Show all ]
Inchi Key	FIADGNVRKBPQEU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H21NS/c1-20-11-8-15(9-12-20)19-16-5-3-2-4-14(16)6-7-18-17(19)10-13-21-18/h2-5,10,13H,6-9,11-12H2,1H3
PubChem CID	27400
ChEMBL	CHEMBL294951
IUPHAR	93
BindingDB	82088
DrugBank	DB06153
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
78859	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
78861	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
548821	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
78863	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
548813	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
78862	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
78860	5-hydroxytryptamine receptor 2B	P30994	Htr2b	Rattus norvegicus (Rat)	479
78866	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
78867	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
78864	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
548812	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
548814	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
548819	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
548822	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
548818	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
548820	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462
78868	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
548817	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
78865	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
548816	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466

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