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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1923416
Molecular formula	C18H20FN3O2
IUPAC name	1-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-[(6-fluoropyridin-3-yl)methyl]piperazine
Molecular weight	329.375
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	2.4
Synonyms	BDBM50358841
Inchi Key	NAIGOHVHPOGNLZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H20FN3O2/c19-18-4-1-14(12-20-18)13-21-5-7-22(8-6-21)15-2-3-16-17(11-15)24-10-9-23-16/h1-4,11-12H,5-10,13H2
PubChem CID	56926587
ChEMBL	CHEMBL1923416
IUPHAR	N/A
BindingDB	50358841
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
218485	5-hydroxytryptamine receptor 2A	P50129	HTR2A	Sus scrofa (Pig)	470
218486	D(1A) dopamine receptor	P50130	DRD1	Sus scrofa (Pig)	446
218484	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
218483	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
527773	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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