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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AC1L1H4K
Molecular formula	C23H32N2O3
IUPAC name	3-hydroxybutan-2-yl 7-methyl-4-propan-2-yl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-carboxylate
Molecular weight	384.52
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.1
Synonyms	CHEMBL53236 BDBM84930 L000859 CAS_60634-51-7 NSC_107989
Inchi Key	JQYLIGHHVGCTPR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H32N2O3/c1-13(2)25-12-16-10-21-19(18-7-6-8-20(25)22(16)18)9-17(11-24(21)5)23(27)28-15(4)14(3)26/h6-8,12-15,17,19,21,26H,9-11H2,1-5H3
PubChem CID	3972
ChEMBL	N/A
IUPHAR	N/A
BindingDB	84930
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
157765	5-hydroxytryptamine receptor 2A	P50129	HTR2A	Sus scrofa (Pig)	470
157769	5-hydroxytryptamine receptor 2A	P50128	HTR2A	Macaca mulatta (Rhesus macaque)	471
556072	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
157766	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
157767	5-hydroxytryptamine receptor 2B	P30994	Htr2b	Rattus norvegicus (Rat)	479
157768	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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