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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2207640
Molecular formula	C28H36N4O
IUPAC name	1-(2-methoxyphenyl)-4-[[3-[(4-methylpiperazin-1-yl)methyl]azulen-1-yl]methyl]piperazine
Molecular weight	444.623
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.0
Synonyms	BDBM50401945
Inchi Key	PLYQWXWXIUOYQJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H36N4O/c1-29-12-14-30(15-13-29)21-23-20-24(26-9-5-3-4-8-25(23)26)22-31-16-18-32(19-17-31)27-10-6-7-11-28(27)33-2/h3-11,20H,12-19,21-22H2,1-2H3
PubChem CID	71450707
ChEMBL	CHEMBL2207640
IUPHAR	N/A
BindingDB	50401945
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
263039	5-hydroxytryptamine receptor 2A	P50129	HTR2A	Sus scrofa (Pig)	470
263035	D(1A) dopamine receptor	P50130	DRD1	Sus scrofa (Pig)	446
263038	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
263041	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
529069	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467
263036	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
263040	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
263037	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
263034	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390

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