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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	5-hydroxytryptamine receptor 2A
Species	Sus scrofa (Pig)
Gene	HTR2A
Synonym	5-HT-2 5-HT-2A 5-HT2A Serotonin receptor 2A
Disease	N/A for non-human GPCRs
Length	470
Amino acid sequence	MDVLCEENTSLSSPTNSFMQLNDDTRLYHNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPPCFSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHRRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQTGQKENSKQDDKATENDCTMVALGKQHSEDAPADNSNTVNEKVSCV
UniProt	P50129
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2490
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL241211
Molecular formula	C27H25Cl2N3O
IUPAC name	N-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]-3-(2-phenylethynyl)benzamide
Molecular weight	478.417
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	6.1
Synonyms	BDBM50221677 N-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)-3-(2-phenylethynyl)benzamide
Inchi Key	IDICUFRCUIOPKM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H25Cl2N3O/c28-24-10-5-11-25(26(24)29)32-18-16-31(17-19-32)15-14-30-27(33)23-9-4-8-22(20-23)13-12-21-6-2-1-3-7-21/h1-11,20H,14-19H2,(H,30,33)
PubChem CID	44436599
ChEMBL	CHEMBL241211
IUPHAR	N/A
BindingDB	50221677
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Activity	0.0 %	PMID17827018	ChEMBL

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