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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2207639
Molecular formula	C27H33N3O2
IUPAC name	4-[[3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]azulen-1-yl]methyl]morpholine
Molecular weight	431.58
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.8
Synonyms	BDBM50401946
Inchi Key	RMDQSWIVOHIFNT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H33N3O2/c1-31-27-10-6-5-9-26(27)30-13-11-28(12-14-30)20-22-19-23(21-29-15-17-32-18-16-29)25-8-4-2-3-7-24(22)25/h2-10,19H,11-18,20-21H2,1H3
PubChem CID	71454294
ChEMBL	CHEMBL2207639
IUPHAR	N/A
BindingDB	50401946
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
299590	5-hydroxytryptamine receptor 2A	P50129	HTR2A	Sus scrofa (Pig)	470
299591	D(1A) dopamine receptor	P50130	DRD1	Sus scrofa (Pig)	446
299594	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
299595	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
529957	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467
299593	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
299597	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
299592	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
299596	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390

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