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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	5-hydroxytryptamine receptor 2A
Species	Sus scrofa (Pig)
Gene	HTR2A
Synonym	5-HT-2 5-HT-2A 5-HT2A Serotonin receptor 2A
Disease	N/A for non-human GPCRs
Length	470
Amino acid sequence	MDVLCEENTSLSSPTNSFMQLNDDTRLYHNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPPCFSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHRRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQTGQKENSKQDDKATENDCTMVALGKQHSEDAPADNSNTVNEKVSCV
UniProt	P50129
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2490
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	1-Isopropyltryptamine
Molecular formula	C13H18N2
IUPAC name	2-(1-propan-2-ylindol-3-yl)ethanamine
Molecular weight	202.301
Hydrogen bond acceptor	1
Hydrogen bond donor	1
XlogP	2.0
Synonyms	2-(1-propan-2-ylindol-3-yl)ethanamine D0ZF1W ZINC4600317 40619-60-1 MolPort-001-788-641 AKOS000276209 SCHEMBL7749047 2-[1-(methylethyl)indol-3-yl]ethylamine GTPL159 N-1-isopropyltryptamine BDBM84943 STK075425 2-[1-(propan-2-yl)-1H-indol-3-yl]ethanamine MCULE-5027387412 AC1NOM56 SBB081239 [ Show all ]
Inchi Key	ARHHZLRATAUACE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C13H18N2/c1-10(2)15-9-11(7-8-14)12-5-3-4-6-13(12)15/h3-6,9-10H,7-8,14H2,1-2H3
PubChem CID	5115445
ChEMBL	N/A
IUPHAR	159
BindingDB	84943
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	5721.0 nM	PMID8510008	BindingDB

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