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You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
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Ligand

Name	desipramine
Molecular formula	C18H22N2
IUPAC name	3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine
Molecular weight	266.388
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	4.9
Synonyms	L001089 5-(3-methylaminopropyl)-10,11-dihydro-5H-dibenzo[b,f]azepine N-(3-Methylaminopropyl)iminobibenzyl 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N-methyl- NCGC00015340-08 ALBB-025959 Norpramin (TN) BSPBio_000405 Prestwick1_000343 CHEMBL72 SPBio_000042 Desipramin STK735144 Desipraminum [INN-Latin] [3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl]methylamine hydrochloride EINECS 200-040-0 KB-232393 10,11-Dihydro-5-(3-methylaminopropyl)-5H-dibenz(b,f)azepine 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine hydrochloride LS-60421 58-28-6 (hydrochloride) NCGC00015340-03 AB00053450_14 NCGC00015340-11 AX8123821 Pertofran (Salt/Mix) CAS-58-28-6 R1868 Spectrum3_000379 UNII-TG537D343B Dimethylimipramine HCYAFALTSJYZDH-UHFFFAOYSA-N (3-(10H,11H-Dibenzo[b,f]azepin-5-yl)propyl)methylamine KBio2_003489 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine MolPort-002-051-955 5H-Dibenzo[b, f]azepine, N-(3-methylaminopropyl)-, 10,11-Dihydro NCGC00015340-06 AJ-26669 NINDS_000190 BRD-K60762818-003-15-3 Pertrofane CHEBI:47781 SCHEMBL34384 Desimipramine Spectrum_000441 Desipramine [INN:BAN] ZX-AN024471 DMI 50475 IDI1_000190 050D475 KBioGR_000928 Lopac-D-3900 5-(gamma-Methylaminopropyl)iminodibenzyl NCGC00015340-01 6943AB NCGC00015340-09 AN-41558 Norpramine BSPBio_002137 Prestwick2_000343 D01UTL SPBio_002326 Desipramina TG537D343B Desmethylimipramine EX-4355 KBio1_000190 3-(10,11-Dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methyl-1-propanamine # 3-(10,11-Dihydro-5H-dibenzo[b,f]azepin-5-yl);-N-methylpropan-1-amine MCULE-5904286906 5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(methylamino)propyl)- NCGC00015340-04 AC-15977 NCGC00015340-13 BDBM35229 Pertofrane (Salt/Mix) CCG-118231 SBB002569 DB01151 Spectrum4_000314 Desipramine (D4) ZERO/006017 DivK1c_000190 HMS3430H03 (3-{2-azatricyclo[9.4.0.0;{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl}propyl)(methyl)amine KBio2_006057 KBioSS_000921 Monodemethylimipramine 5H-Dibenz[b,f]azepine, 10,11-dihydro-5-[3-(methylamino)propyl]- NCGC00015340-07 AKOS001681456 Norimipramine BRN 1432747 Prestwick0_000343 Sertofran Desimpramine ST052019 desipraminum [3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl]methylamine DTXSID6022896 Imipramine, demethyl- 10, 11-Dihydro-N-methyl-5H-dibez[b,f]azepine-5-propanamine Lopac0_000358 50-47-5 NCGC00015340-02 AB00053450 NCGC00015340-10 API0009063 Pentofran C06943 Prestwick3_000343 D07791 Spectrum2_000091 Desipramina [INN-Spanish] Treyzafagit Dezipramine GTPL2399 KBio2_000921 3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methyl-propan-1-amine Methylaminopropyliminodibenzyl 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N-methyl- NCGC00015340-05 AC1L1EXQ NCGC00024375-04 BPBio1_000447 Pertofrane (TN) CCRIS 7091 SBI-0050346.P004 Demethylimipramine Spectrum5_000833 Desipramine (INN) ZINC1530611 DMI (pharmaceutical) HSDB 3052 KBio3_001357 [ Show all ]
Inchi Key	HCYAFALTSJYZDH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H22N2/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20/h2-5,7-10,19H,6,11-14H2,1H3
PubChem CID	2995
ChEMBL	CHEMBL72
IUPHAR	N/A
BindingDB	35229
DrugBank	DB01151
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
111728	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
111751	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
111734	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
111727	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
555902	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
111739	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
111744	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
111733	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
555903	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
111746	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
111748	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
111750	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
111738	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
111731	Alpha-2C adrenergic receptor	P22086	Adra2c	Rattus norvegicus (Rat)	458
111747	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462
111745	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
111732	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
460223	Beta-2 adrenergic receptor	P10608	Adrb2	Rattus norvegicus (Rat)	418
111730	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
111741	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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