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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Skf-77434
Molecular formula	C19H21NO2
IUPAC name	5-phenyl-3-prop-2-enyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol
Molecular weight	295.382
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	3.6
Synonyms	104422-04-0 AC1L1B1E N-allyl-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine SKF 38393, N-allyl-, hydrobromide 3-allyl-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepine-7,8-diol AKOS030239137 DTXSID3043817 NCGC00025249-02 (+)-7,8-di-hydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepine 5-phenyl-3-prop-2-enyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol CCG-205217 LS-171920 SCHEMBL7390591 1H-3-Benzazepine-7,8-diol, 2,3,4,5-tetrahydro-1-phenyl-3-(2-propenyl)- AC1Q79PZ CHEMBL288090 NCGC00015915-03 SKF 77434 3-Allyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrochloride BDBM50004918 L001232 PDSP1_001525 (+/-)-APD3-Allyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol CHEBI:63988 N-allyl-1-phenyl-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol SK&F 77434 1-phenyl-3-prop-2-en-1-yl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol 1H-3-Benzazepine-7,8-diol,2,3,4,5-tetrahydro-1-phenyl-3-(2-propen-1-yl)- ACMC-20calx CTK4A3038 NCGC00015915-04 SKF-77,434 3-Allyl-2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine BRD-A64227845-004-02-8 Lopac0_001143 PDSP2_001509 (+/-)-SKF 38393, N-allyl-, hydrobromide [ Show all ]
Inchi Key	QBUVZVXIRYFENV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H21NO2/c1-2-9-20-10-8-15-11-18(21)19(22)12-16(15)17(13-20)14-6-4-3-5-7-14/h2-7,11-12,17,21-22H,1,8-10,13H2
PubChem CID	1241
ChEMBL	CHEMBL288090
IUPHAR	N/A
BindingDB	50004918
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
274464	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
556538	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
274462	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
274468	Alpha-2C adrenergic receptor	P22086	Adra2c	Rattus norvegicus (Rat)	458
274461	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
274463	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
274465	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
274467	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
274466	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400

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