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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL43345
Molecular formula	C17H17NO2
IUPAC name	(6aR,12bR)-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine-10,11-diol
Molecular weight	267.328
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	2.5
Synonyms	(6aR,12bR)-5,6,6a,7,8,12b-Hexahydrobenzo[a]phenanthridine-10,11-diol ZINC26746099 BDBM50010685 (+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine Dihydrexidine, DHX 5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol (6aR,12bR)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol SCHEMBL13038957 [ Show all ]
Inchi Key	BGOQGUHWXBGXJW-PBHICJAKSA-N
Inchi ID	InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17+/m1/s1
PubChem CID	14708665
ChEMBL	CHEMBL43345
IUPHAR	N/A
BindingDB	50010685
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
555564	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
23228	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
23226	Alpha-2C adrenergic receptor	P22086	Adra2c	Rattus norvegicus (Rat)	458
459414	Beta-2 adrenergic receptor	P10608	Adrb2	Rattus norvegicus (Rat)	418
23229	Bombesin receptor subtype-3	Q8K418	Brs3	Rattus norvegicus (Rat)	399
23230	Cholecystokinin receptor type A	P30551	Cckar	Rattus norvegicus (Rat)	444
23227	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
23225	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
555563	Gamma-aminobutyric acid type B receptor subunit 1	Q9Z0U4	Gabbr1	Rattus norvegicus (Rat)	991

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