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Name | GR 113808 |
---|---|
Molecular formula | C19H27N3O4S |
IUPAC name | [1-[2-(methanesulfonamido)ethyl]piperidin-4-yl]methyl 1-methylindole-3-carboxylate |
Molecular weight | 393.502 |
Hydrogen bond acceptor | 6 |
Hydrogen bond donor | 1 |
XlogP | 1.7 |
Synonyms | D08JLW GR113808 Lopac-G-5918 NCGC00015477-02 PDSP1_000842 [ Show all ] |
Inchi Key | MOZPSIXKYJUTKI-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C19H27N3O4S/c1-21-13-17(16-5-3-4-6-18(16)21)19(23)26-14-15-7-10-22(11-8-15)12-9-20-27(2,24)25/h3-6,13,15,20H,7-12,14H2,1-2H3 |
PubChem CID | 119376 |
ChEMBL | CHEMBL33884 |
IUPHAR | 247 |
BindingDB | 29525 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
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GLASS ID | Name | UniProt | Gene | Species | Length |
---|---|---|---|---|---|
210873 | 5-hydroxytryptamine receptor 2A | P28223 | HTR2A | Homo sapiens (Human) | 471 |
556308 | 5-hydroxytryptamine receptor 2A | P14842 | Htr2a | Rattus norvegicus (Rat) | 471 |
210874 | 5-hydroxytryptamine receptor 2B | P41595 | HTR2B | Homo sapiens (Human) | 481 |
210853 | 5-hydroxytryptamine receptor 2C | P08909 | Htr2c | Rattus norvegicus (Rat) | 460 |
210855 | 5-hydroxytryptamine receptor 2C | P28335 | HTR2C | Homo sapiens (Human) | 458 |
210852 | 5-hydroxytryptamine receptor 4 | Q13639 | HTR4 | Homo sapiens (Human) | 388 |
210859 | 5-hydroxytryptamine receptor 4 | O70528 | HTR4 | Cavia porcellus (Guinea pig) | 388 |
210861 | 5-hydroxytryptamine receptor 4 | Q62758 | Htr4 | Rattus norvegicus (Rat) | 406 |
554335 | 5-hydroxytryptamine receptor 4 | P97288 | Htr4 | Mus musculus (Mouse) | 388 |
210864 | Adenosine receptor A1 | P25099 | Adora1 | Rattus norvegicus (Rat) | 326 |
210854 | Adenosine receptor A2a | P30543 | Adora2a | Rattus norvegicus (Rat) | 410 |
210866 | Alpha-1A adrenergic receptor | P43140 | Adra1a | Rattus norvegicus (Rat) | 466 |
210872 | Alpha-2C adrenergic receptor | P22086 | Adra2c | Rattus norvegicus (Rat) | 458 |
210856 | B1 bradykinin receptor | P97583 | Bdkrb1 | Rattus norvegicus (Rat) | 337 |
210858 | Beta-1 adrenergic receptor | P18090 | Adrb1 | Rattus norvegicus (Rat) | 466 |
210877 | Beta-2 adrenergic receptor | Q8K4Z4 | Adrb2 | Cavia porcellus (Guinea pig) | 418 |
210865 | Bombesin receptor subtype-3 | Q8K418 | Brs3 | Rattus norvegicus (Rat) | 399 |
210871 | D(1A) dopamine receptor | P18901 | Drd1 | Rattus norvegicus (Rat) | 446 |
556309 | D(2) dopamine receptor | P61169 | Drd2 | Rattus norvegicus (Rat) | 444 |
556310 | Gamma-aminobutyric acid type B receptor subunit 1 | Q9Z0U4 | Gabbr1 | Rattus norvegicus (Rat) | 991 |
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