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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Reboxetine
Molecular formula	C19H23NO3
IUPAC name	(2S)-2-[(S)-(2-ethoxyphenoxy)-phenylmethyl]morpholine
Molecular weight	313.397
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.0
Synonyms	Tocris-1982 (2S)-2-[(S)-(2-ETHOXYPHENOXY)BENZYL]MORPHOLINE 98819-76-2 CHEBI:125535 DB12395 Morpholine, 2-((S)-(2-ethoxyphenoxy)phenylmethyl)-, (2S)- Reboxitine Vestra (+-)-(2R)-2-((alphaR)-alpha-(o-Ethoxyphenoxy)benzyl)morpholine (S,S)-reboxetine AKOS027393802 D01NJT Esreboxetine (USAN/INN) Norebox (TN) Solvex (2S)-2-[(S)-(2-ethoxyphenoxy)-phenyl-methyl]morpholine 819S762 BDBM35226 Davedax L8S50ZY490 Prolift Reboxetine (INN) UNII-947S0YZ36I component CBQGYUDMJHNJBX-OALUTQOASA-N (2S)-2-[(S)-2-ethoxyphenoxy(phenyl)methyl]morpholine AC1L2442 CHEMBL180101 Edronax (TN) NCGC00025335-01 S-Reboxetine Vestra (TN) (2R)-2-[(R)-(2-ethoxyphenoxy)-phenylmethyl]morpholine 2-((2-ethoxyphenoxy)benzyl)morpholine methanesulfonate AN-4973 D09340 Esreboxetine [USAN:INN] PNU 165442g Prolift (TN) Solvex (TN) (2S)-2-[(S)-(2-ethoxyphenoxy)-phenylmethyl]morpholine 98769-81-4 BRD-K32814891-001-01-1 Davedax (TN) LS-178388 Reboxetine [INN] UNII-L8S50ZY490 (+)-(2S)-2-((S)-(2-Ethoxyphenoxy)phenylmethyl)morpholine (S,S)-( )-Reboxetine AJ-08295 CTK5I0084 Esreboxetine Norebox SCHEMBL34534 ZINC6923 (2R)-2-[(S)-(2-ethoxyphenoxy)-phenylmethyl]morpholine API0006066 D0N8FQ GTPL4808 PNU-165442G [ Show all ]
Inchi Key	CBQGYUDMJHNJBX-OALUTQOASA-N
Inchi ID	InChI=1S/C19H23NO3/c1-2-21-16-10-6-7-11-17(16)23-19(15-8-4-3-5-9-15)18-14-20-12-13-22-18/h3-11,18-20H,2,12-14H2,1H3/t18-,19-/m0/s1
PubChem CID	65856
ChEMBL	N/A
IUPHAR	N/A
BindingDB	35226
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
38116	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
38113	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
38112	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
38117	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
38114	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
38115	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
555618	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
38111	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
38110	Alpha-2C adrenergic receptor	P22086	Adra2c	Rattus norvegicus (Rat)	458
555619	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
555617	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400

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