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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCH 23390
Molecular formula	C17H18ClNO
IUPAC name	8-chloro-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol
Molecular weight	287.787
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	4.0
Synonyms	3-Methyl-5-phenyl-8-chloro-2,3,4,5-tetrahydro-1H-3-benzazepine-7-ol AC1L1JFI CTK3F4102 NSC_5018 SCHEMBL5722114 8-chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepin-7-ol BDBM86180 GOTMKOSCLKVOGG-UHFFFAOYSA-N Sch 23388 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl- L000549 SCH-23390 7-chloro-3-methyl-1-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol AC1Q3LCZ D09GBZ PDSP1_001507 [3H]-SCH23390 CAS_87075-17-0 GTPL943 2,3,4,5-Tetrahydro-8-chloro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol (R)- 95191-55-2 CHEMBL13668 LS-28022 SCH23390 8-chloro-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol ACMC-20dd35 D0L8PI PDSP2_001491 [3H]SCH-23390 1H-3-Benzazepin-7-ol, 2,3,4,5-tetrahydro-8-chloro-3-methyl-5-phenyl-, (R)- CHEBI:73297 GTPL946 Sch-23388 [ Show all ]
Inchi Key	GOTMKOSCLKVOGG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3
PubChem CID	5018
ChEMBL	CHEMBL13668
IUPHAR	946, 943
BindingDB	86180
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
101551	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
101555	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
101550	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
555852	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
101546	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
101552	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
101549	Alpha-2C adrenergic receptor	P22086	Adra2c	Rattus norvegicus (Rat)	458
101542	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
101544	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
101547	D(1A) dopamine receptor	Q95136	DRD1	Bos taurus (Bovine)	446
101543	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
101554	D(1B) dopamine receptor	P25115	Drd5	Rattus norvegicus (Rat)	475
101541	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
555851	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
101545	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
101548	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467
101553	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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