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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL303334
Molecular formula	C15H20Br2N2O3
IUPAC name	3,5-dibromo-N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-hydroxy-6-methoxybenzamide
Molecular weight	436.144
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	3.0
Synonyms	AC1MHWAJ 3,5-Dibromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide FLA-659 84226-15-3 BDBM50026053 3,5-dibromo-N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-hydroxy-6-methoxybenzamide PDSP2_000911 A 36569 [ Show all ]
Inchi Key	JNFBCMWINGLNPB-VIFPVBQESA-N
Inchi ID	InChI=1S/C15H20Br2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1
PubChem CID	3033771
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50026053
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
556058	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
556060	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
155059	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
155060	Alpha-2C adrenergic receptor	P22086	Adra2c	Rattus norvegicus (Rat)	458
460619	Beta-2 adrenergic receptor	P10608	Adrb2	Rattus norvegicus (Rat)	418
155057	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
556059	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
155056	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486
155058	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466

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