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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Robalzotan BNAD 299 HCL
Molecular formula	C18H23FN2O2
IUPAC name	3-[di(cyclobutyl)amino]-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide
Molecular weight	318.392
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.8
Synonyms	CAS_3055171 BCP28753 L000427 3-(Dicyclobutylamino)-8-fluoro-3,4-dihydro-2H-1-benzopyran-5-carboxamide SCHEMBL4811762 BDBM85190 NSC_3055171 [ Show all ]
Inchi Key	MQTUXRKNJYPMCG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H23FN2O2/c19-16-8-7-14(18(20)22)15-9-13(10-23-17(15)16)21(11-3-1-4-11)12-5-2-6-12/h7-8,11-13H,1-6,9-10H2,(H2,20,22)
PubChem CID	12016890
ChEMBL	N/A
IUPHAR	N/A
BindingDB	85190
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
212015	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
212012	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
556314	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
212007	5-hydroxytryptamine receptor 6	P31388	Htr6	Rattus norvegicus (Rat)	436
556313	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
212010	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
212014	Alpha-2C adrenergic receptor	P22086	Adra2c	Rattus norvegicus (Rat)	458
461070	Beta-2 adrenergic receptor	P10608	Adrb2	Rattus norvegicus (Rat)	418
212009	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
212013	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
212011	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
212008	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486
212005	Histamine H2 receptor	P47747	HRH2	Cavia porcellus (Guinea pig)	359
212006	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466

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