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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Alpha-2C adrenergic receptor
Species	Rattus norvegicus (Rat)
Gene	Adra2c
Synonym	alpha2C-adrenoceptor alpha2-C4 Alpha-2CAR alpha-2C adrenoreceptor Alpha-2C adrenoceptor alpha-2C adrenergic receptor alpha-2 adrenergic receptor subtype C4 adrenergic receptor Adrenergic alpha2C- receptor class I ADRA2RL2 ADRA2L2 Adra-2c [ Show all ]
Disease	N/A for non-human GPCRs
Length	458
Amino acid sequence	MASPALAAALAAAAAEGPNGSDAGEWGSGGGANASGTDWGPPPGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSFYRRPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRGPAGPDGASPTTENGLGKAAGENGHCAPPRTEVEPDESSAAERRRRRGALRRGGRRREGAEGDTGSADGPGPGLAAEQGARTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQLPEPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ
UniProt	P22086
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL314
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	GTP gamma-4-azidoanilide
Molecular formula	C16H20N9O13P3
IUPAC name	[[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-N-(4-azidophenyl)phosphonamidic acid
Molecular weight	639.307
Hydrogen bond acceptor	18
Hydrogen bond donor	8
XlogP	-1.9
Synonyms	BDBM85783 GTP-gamma-Azidoanilidate 60869-76-3 gamma-(p-Azidoanilide)-GTP Guanosine 5'-(trihydrogen diphosphate), monoanhydride with (4-azidophenyl)phosphoramidic acid AC1LCUW4 [[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-N-(4-azidophenyl)phosphonamidic acid 4-Azidoanilido-5'-GTP Brimonidine GTP Guanosine 5' triphosphate [Gamma] 4-Azidoanilide GTP Azidoanilide Guanosine 5'-(trihydrogen diphosphate), P'-anhydride with (4-azidophenyl)phosphoramidic acid (9CI) Alpha-32P-labelled azidoanilido analog of GTP GTP gamma-p-Azidoanilide 4-Azidoanilido-GTP DTXSID60209714 Guanosine 5' [Alpha-32P] triphosphate [Gamma] 4-Azidoanilide AAGTP GTP Gamma AA Guanosine 5'-(trihydrogen diphosphate-P-32P), P'-anhydride with (4-azidophenyl)phosphoramidic acid (9CI) [ Show all ]
Inchi Key	OIEPSMNDOZUCOC-SDBHATRESA-N
Inchi ID	InChI=1S/C16H20N9O13P3/c17-16-20-13-10(14(28)21-16)19-6-25(13)15-12(27)11(26)9(36-15)5-35-40(31,32)38-41(33,34)37-39(29,30)23-8-3-1-7(2-4-8)22-24-18/h1-4,6,9,11-12,15,26-27H,5H2,(H,31,32)(H,33,34)(H2,23,29,30)(H3,17,20,21,28)/t9-,11-,12-,15-/m1/s1
PubChem CID	135450577
ChEMBL	N/A
IUPHAR	N/A
BindingDB	85783
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
Ki	1.6 nM	PMID11275272	BindingDB

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