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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2111783
Molecular formula	C17H20FN3S
IUPAC name	(6R)-8-fluoro-6-(4-methylpiperazin-1-yl)-5,6-dihydropyrrolo[2,1-b][1,3]benzothiazepine
Molecular weight	317.426
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	2.6
Synonyms	BDBM50409601 (9R)-7-Fluoro-9-(4-methylpiperazino)-9,10-dihydro-4-thia-10a-azabenzo[f]azulene
Inchi Key	FNXVFVIKVBLUPH-HNNXBMFYSA-N
Inchi ID	InChI=1S/C17H20FN3S/c1-19-7-9-20(10-8-19)15-12-21-6-2-3-17(21)22-16-5-4-13(18)11-14(15)16/h2-6,11,15H,7-10,12H2,1H3/t15-/m0/s1
PubChem CID	11023546
ChEMBL	CHEMBL2111783
IUPHAR	N/A
BindingDB	50409601
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
83018	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
83016	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
83014	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
83017	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446
83019	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486
83015	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460

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