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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Histamine H1 receptor
Species	Rattus norvegicus (Rat)
Gene	Hrh1
Synonym	H1 receptor H1R HH1R Hisr
Disease	N/A for non-human GPCRs
Length	486
Amino acid sequence	MSFANTSSTFEDKMCEGNRTAMASPQLLPLVVVLSSISLVTVGLNLLVLYAVHSERKLHTVGNLYIVSLSVADLIVGAVVMPMNILYLIMTKWSLGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLRYLRYRTKTRASATILGAWFFSFLWVIPILGWHHFMPPAPELREDKCETDFYNVTWFKIMTAIINFYLPTLLMLWFYVKIYKAVRRHCQHRQLTNGSLPSFSELKLRSDDTKEGAKKPGRESPWGVLKRPSRDPSVGLDQKSTSEDPKMTSPTVFSQEGERETRPCFRLDIMQKQSVAEGDVRGSKANDQALSQPKMDEQSLNTCRRISETSEDQTLVDQQSFSRTTDSDTSIEPGPGRVKSRSGSNSGLDYIKITWKRLRSHSRQYVSGLHLNRERKAAKQLGFIMAAFILCWIPYFIFFMVIAFCKSCCSEPMHMFTIWLGYINSTLNPLIYPLCNENFKKTFKKILHIRS
UniProt	P31390
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4701
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	LR 5182
Molecular formula	C17H24Cl3N
IUPAC name	[(2R,3S)-3-(3,4-dichlorophenyl)-2-bicyclo[2.2.2]octanyl]methyl-dimethylazanium;chloride
Molecular weight	348.736
Hydrogen bond acceptor	1
Hydrogen bond donor	1
XlogP	None
Synonyms	62374-00-9 (+)-cis-2-(3,4-Dichlorophenyl)-3-dimethylaminomethylbicyclo(2.2.2)octane, hydrochloride Bicyclo(2.2.2)octane-2-methylamine, 3-(3,4-dichlorophenyl)-N,N-dimethyl-, hydrochloride, (Z)- LS-43799 62373-97-1 cis-3-(3,4-Dichlorophenyl)-N,N-dimethylbicyclo(2.2.2)octane-2-methanamine hydrochloride LS-43797 [(2R,3S)-3-(3,4-dichlorophenyl)-2-bicyclo[2.2.2]octanyl]methyl-dimethylazanium chloride (-)-cis-2-(3,4-Dichlorophenyl)-3-dimethylaminomethylbicyclo(2.2.2)octane, hydrochloride Bicyclo(2.2.2)octane-2-methylamine, 3-(3,4-dichlorophenyl)-N,N-dimethyl-, hydrochloride, (Z)-(+)- 62373-99-3 EW5182 AC1L2B00 LS-43798 (Z)-3-(3,4-Dichlorophenyl)-N,N-dimethylbicyclo(2.2.2)octane-2-methylamine hydrochloride Bicyclo(2.2.2)octane-2-methylamine, 3-(3,4-dichlorophenyl)-N,N-dimethyl-, hydrochloride, (Z)-(-)- [ Show all ]
Inchi Key	CWRRQXXGIKGNJA-PQTJMFGHSA-N
Inchi ID	InChI=1S/C17H23Cl2N.ClH/c1-20(2)10-14-11-3-5-12(6-4-11)17(14)13-7-8-15(18)16(19)9-13;/h7-9,11-12,14,17H,3-6,10H2,1-2H3;1H/t11?,12?,14-,17-;/m1./s1
PubChem CID	44023
ChEMBL	N/A
IUPHAR	N/A
BindingDB	82084
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	Partition coefficient log P of this ligand is not available.

Experimental Data

Parameter	Value	Reference	Database source
Ki	2000.0 nM	PMID6123593	BindingDB

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