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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL141432
Molecular formula	C20H21ClN2O
IUPAC name	N-[(3Z)-3-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)propyl]-N-methylacetamide
Molecular weight	340.851
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	3.5
Synonyms	N-[3-[[(Z)-8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin]-11-ylidene]propyl]-N-methylacetamide BDBM50007474 N-[3-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-propyl]-N-methyl-acetamide(Z isomer)
Inchi Key	JHOJSIPGICNRRG-SWNXQHNESA-N
Inchi ID	InChI=1S/C20H21ClN2O/c1-14(24)23(2)12-4-6-19-18-10-9-17(21)13-16(18)8-7-15-5-3-11-22-20(15)19/h3,5-6,9-11,13H,4,7-8,12H2,1-2H3/b19-6-
PubChem CID	44361141
ChEMBL	CHEMBL141432
IUPHAR	N/A
BindingDB	50007474
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
151178	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486
151179	Platelet-activating factor receptor	P25105	PTAFR	Homo sapiens (Human)	342

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