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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL334127
Molecular formula	C21H21ClN2O
IUPAC name	1-[4-(14-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]ethanone
Molecular weight	352.862
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	4.4
Synonyms	SCHEMBL8880503 5,6-Dihydro-11-(1-acetyl-4-piperidinylidene)-9-chloro-11H-benzo[5,6]cyclohepta[1,2-b]pyridine 1-[4-(9-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-ethanone BDBM50007460
Inchi Key	HKOAZVBUNRGWIO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H21ClN2O/c1-14(25)24-11-8-16(9-12-24)20-19-13-18(22)7-6-15(19)4-5-17-3-2-10-23-21(17)20/h2-3,6-7,10,13H,4-5,8-9,11-12H2,1H3
PubChem CID	14885627
ChEMBL	CHEMBL334127
IUPHAR	N/A
BindingDB	50007460
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
117366	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486
117365	Platelet-activating factor receptor	P25105	PTAFR	Homo sapiens (Human)	342

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