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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL367045
Molecular formula	C17H19N3S
IUPAC name	6-(4-methylpiperazin-1-yl)pyrrolo[2,1-b][1,3]benzothiazepine
Molecular weight	297.42
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	3.0
Synonyms	L001663 9-(4-Methylpiperazino)-4-thia-10a-azabenzo[f]azulene SCHEMBL3286899 9-(4-Methyl-piperazin-1-yl)-4-thia-10a-aza-benzo[f]azulene BDBM50137976 JFLBTRDHDHTNGX-UHFFFAOYSA-N 395073-74-2 9-(4-Methylpiperazin-1-yl) Pyrolo [2,1-b][1,3]benzothiazepine [ Show all ]
Inchi Key	JFLBTRDHDHTNGX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H19N3S/c1-18-9-11-19(12-10-18)15-13-20-8-4-7-17(20)21-16-6-3-2-5-14(15)16/h2-8,13H,9-12H2,1H3
PubChem CID	9796255
ChEMBL	CHEMBL367045
IUPHAR	N/A
BindingDB	50137976
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
149701	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
149707	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
149706	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
149702	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
149703	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
149700	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446
149704	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
149705	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486
149699	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460

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