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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL60524
Molecular formula	C19H19ClN4O
IUPAC name	3-(4-chlorophenyl)-N-[2-(1H-imidazol-5-yl)ethyl]-3-pyridin-2-ylpropanamide
Molecular weight	354.838
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	2.6
Synonyms	N-[2-(4-Imidazolyl)ethyl]-3-(2-pyridinyl)-3-(4-chlorophenyl)propionamide 3-(4-Chloro-phenyl)-N-[2-(1H-imidazol-4-yl)-ethyl]-3-pyridin-2-yl-propionamide SCHEMBL14040781 BDBM50128881
Inchi Key	DYSJRNDWTMFCAH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H19ClN4O/c20-15-6-4-14(5-7-15)17(18-3-1-2-9-22-18)11-19(25)23-10-8-16-12-21-13-24-16/h1-7,9,12-13,17H,8,10-11H2,(H,21,24)(H,23,25)
PubChem CID	9924758
ChEMBL	CHEMBL60524
IUPHAR	N/A
BindingDB	50128881
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
72239	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486
72238	Histamine H3 receptor	Q9JI35	HRH3	Cavia porcellus (Guinea pig)	445

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