You can:
| Name | Histamine H3 receptor |
|---|---|
| Species | Cavia porcellus (Guinea pig) |
| Gene | HRH3 |
| Synonym | H3R HH3R |
| Disease | N/A for non-human GPCRs |
| Length | 445 |
| Amino acid sequence | MERAPPDGLMNASGALAGEAAAAAGGARTFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGVFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTSSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMVLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGAREAGPDPLPEAQSSPPQPPPGCWGCWPKGQGESMPLHRYGVGEAGPGAEAGEAALGGGSGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHSSLEHCWK |
| UniProt | Q9JI35 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL5076 |
| IUPHAR | N/A |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 265 |  CHEMBL204705 | C24H34N4O2 | 410.562 | 4 / 1 | 2.9 | Yes |
| 1781 |  ciproxifan | C16H18N2O2 | 270.332 | 3 / 1 | 2.5 | Yes |
| 2205 |  CHEMBL458722 | C26H38N2 | 378.604 | 2 / 0 | 6.3 | No |
| 2937 |  BDBM50070217 | C15H17BrN4O3 | 381.23 | 5 / 2 | 1.9 | Yes |
| 2957 |  CID 44370594 | C14H21N3O6 | 327.337 | 7 / 4 | N/A | N/A |
| 4928 |  CHEMBL104300 | C20H30ClN3O2S | 411.989 | 4 / 2 | 5.4 | No |
| 5675 |  AC1L1HUK | C29H28ClN3O4 | 518.01 | 4 / 2 | 5.2 | No |
| 6496 |  CHEMBL128585 | C17H21N3O2 | 299.374 | 3 / 2 | 2.7 | Yes |
| 7069 |  CHEMBL204606 | C24H35N3O2 | 397.563 | 4 / 1 | 4.9 | Yes |
| 7803 |  CHEMBL2283088 | C28H54Cl3N3O | 555.11 | 4 / 3 | N/A | No |
| 8287 |  CHEMBL377500 | C13H17N5OS | 291.373 | 4 / 2 | 1.4 | Yes |
| 8413 |  CHEMBL458507 | C26H36N2O | 392.587 | 2 / 0 | 5.4 | No |
| 9334 |  CHEMBL1222420 | C17H26N4O | 302.422 | 4 / 0 | 0.5 | Yes |
| 9569 |  CHEMBL53412 | C23H31N3O2S | 413.58 | 4 / 2 | 6.0 | No |
| 9594 |  CHEMBL444827 | C21H23ClN4O | 382.892 | 3 / 2 | 3.3 | Yes |
| 10741 |  CHEMBL3287723 | C25H32O7 | 444.524 | 7 / 2 | 5.7 | No |
| 11207 |  CHEMBL1222865 | C29H40N6O2 | 504.679 | 5 / 0 | 2.3 | No |
| 11244 |  CHEMBL494982 | C17H21N3O | 283.375 | 3 / 1 | 2.9 | Yes |
| 11874 |  CHEMBL457006 | C21H28N2 | 308.469 | 2 / 0 | 4.1 | Yes |
| 11984 |  CHEMBL68764 | C17H25N3O2S | 335.466 | 4 / 2 | 3.4 | Yes |
| 12140 |  CHEMBL425765 | C23H33N5O2 | 411.55 | 5 / 2 | 2.0 | Yes |
| 12271 |  CHEMBL39603 | C21H25NO2 | 323.436 | 3 / 0 | 3.8 | Yes |
| 13735 |  CHEMBL2437432 | C28H31FN8O2 | 530.608 | 8 / 1 | 1.8 | No |
| 13806 |  CHEMBL2283091 | C23H44Cl3N3O | 484.975 | 4 / 4 | N/A | N/A |
| 14783 |  CHEMBL1223152 | C28H31N5O2 | 469.589 | 4 / 1 | 3.1 | Yes |
| 15541 |  CHEMBL424675 | C24H36N4O | 396.579 | 4 / 1 | 3.8 | Yes |
| 15568 |  CHEMBL205129 | C25H38N4O | 410.606 | 4 / 1 | 4.3 | Yes |
| 16728 |  CHEMBL2283102 | C15H28Cl3N3O | 372.759 | 4 / 4 | N/A | N/A |
| 17687 |  CHEMBL76002 | C16H25ClN4 | 308.854 | 2 / 2 | 2.6 | Yes |
| 17948 |  CHEMBL312613 | C14H17N3 | 227.311 | 2 / 2 | 1.9 | Yes |
| 18810 |  CHEMBL306077 | C11H20N4S | 240.369 | 2 / 3 | 1.2 | Yes |
| 19722 |  CHEMBL131021 | C20H24N2O6 | 388.42 | 7 / 3 | N/A | N/A |
| 21677 |  CHEMBL290613 | C22H25NO6 | 399.443 | 7 / 2 | N/A | N/A |
| 21758 |  CHEMBL99518 | C15H24N6 | 288.399 | 3 / 3 | 2.4 | Yes |
| 23133 |  CHEMBL105495 | C17H25ClN4O2S | 384.923 | 5 / 3 | 3.5 | Yes |
| 23577 |  CHEMBL174609 | C12H14N4O | 230.271 | 2 / 3 | 0.6 | Yes |
| 24185 |  CHEMBL44220 | C10H18N4S | 226.342 | 2 / 3 | 0.8 | Yes |
| 24431 |  CHEMBL128513 | C19H22N2O6 | 374.393 | 7 / 3 | N/A | N/A |
| 24920 |  CHEMBL75322 | C11H12N4 | 200.245 | 2 / 3 | 1.0 | Yes |
| 25251 |  CHEMBL1223074 | C25H31N5O2 | 433.556 | 4 / 1 | 2.8 | Yes |
| 25582 |  CHEMBL203263 | C15H20ClN3 | 277.796 | 2 / 2 | 3.1 | Yes |
| 26155 |  CHEMBL173599 | C19H20N4O2 | 336.395 | 3 / 3 | 2.5 | Yes |
| 26170 |  CHEMBL474716 | C14H24N4OS | 296.433 | 5 / 0 | 1.9 | Yes |
| 26902 |  CHEMBL305174 | C11H15N3O2S2 | 285.38 | 5 / 2 | 1.7 | Yes |
| 26968 |  CHEMBL14868 | C31H41N3O | 471.689 | 4 / 1 | 7.3 | No |
| 27477 |  CHEMBL204640 | C22H27N5O | 377.492 | 5 / 1 | 3.1 | Yes |
| 27736 |  CHEMBL35869 | C24H30N2O6 | 442.512 | 8 / 2 | N/A | N/A |
| 28303 |  CHEMBL301176 | C15H15N3O2S | 301.364 | 4 / 2 | 2.3 | Yes |
| 28669 |  CHEMBL61348 | C21H24ClN5 | 381.908 | 3 / 2 | 3.0 | Yes |
| 29319 |  CID 44370355 | C16H25N3O6 | 355.391 | 7 / 4 | N/A | N/A |
| 30040 |  Histaprodifen | C20H23N3 | 305.425 | 2 / 2 | 3.5 | Yes |
| 30198 |  SCHEMBL14542291 | C22H21NO3 | 347.414 | 3 / 0 | 4.3 | Yes |
| 30646 |  FUB-349 | C13H16N2 | 200.285 | 1 / 1 | 3.2 | Yes |
| 30725 |  76721-87-4 | C7H13N3 | 139.202 | 2 / 2 | 0.4 | Yes |
| 32134 |  aspirin | C9H8O4 | 180.159 | 4 / 1 | 1.2 | Yes |
| 32460 |  CHEMBL58549 | C20H21ClN4O | 368.865 | 3 / 2 | 3.0 | Yes |
| 35820 |  CHEMBL356449 | C27H30N4 | 410.565 | 3 / 2 | 4.9 | Yes |
| 35986 |  CHEMBL169026 | C15H14ClN3S | 303.808 | 3 / 1 | 4.0 | Yes |
| 36325 |  CHEMBL72174 | C13H16N4S | 260.359 | 2 / 3 | 2.0 | Yes |
| 36657 |  CHEMBL104364 | C14H18BrN3O2S | 372.281 | 4 / 2 | 2.4 | Yes |
| 37931 |  CHEMBL50873 | C16H19IN4S | 426.32 | 2 / 2 | 2.7 | Yes |
| 37958 |  CHEMBL416053 | C27H36N2O5 | 468.594 | 7 / 2 | N/A | N/A |
| 39721 |  CHEMBL83862 | C8H13N3 | 151.213 | 2 / 2 | 0.3 | Yes |
| 40311 |  Aripiprazole | C23H27Cl2N3O2 | 448.388 | 4 / 1 | 4.6 | Yes |
| 555632 |  UNII-67WL275ISI | C26H34N2O3 | 422.569 | 4 / 0 | 4.4 | Yes |
| 41308 |  CHEMBL373000 | C18H23ClN4O | 346.859 | 3 / 2 | 2.6 | Yes |
| 41424 |  CHEMBL458718 | C26H40N2 | 380.62 | 2 / 0 | 6.8 | No |
| 41939 |  CHEMBL73370 | C11H20N4S | 240.369 | 2 / 3 | 1.3 | Yes |
| 44325 |  CHEMBL107083 | C14H19ClN4O2S | 342.842 | 5 / 3 | 2.0 | Yes |
| 44730 |  CHEMBL511850 | C23H30N2O | 350.506 | 3 / 0 | 3.7 | Yes |
| 45563 |  CHEMBL336499 | C14H23N3O2 | 265.357 | 3 / 2 | 2.7 | Yes |
| 45715 |  CHEMBL88048 | C20H18N4O3S2 | 426.509 | 6 / 2 | 3.8 | Yes |
| 45775 |  23981-80-8 | C14H14O3 | 230.263 | 3 / 1 | 3.3 | Yes |
| 45796 |  CHEMBL455266 | C20H19N3O | 317.392 | 3 / 1 | 3.5 | Yes |
| 46696 |  CHEMBL48528 | C16H19ClN4S | 334.866 | 2 / 2 | 2.7 | Yes |
| 46939 |  CHEMBL1222719 | C29H39N5O3 | 505.663 | 5 / 0 | 2.6 | No |
| 47553 |  CHEMBL2297876 | C22H37Br3N4S | 629.338 | 5 / 3 | N/A | No |
| 47565 |  GR-175737 | C14H13ClN4O | 288.735 | 4 / 1 | 3.2 | Yes |
| 48032 |  CHEMBL308058 | C17H17N5 | 291.358 | 3 / 2 | 1.6 | Yes |
| 48343 |  CHEMBL439689 | C23H36N4O | 384.568 | 4 / 1 | 3.8 | Yes |
| 48574 |  CHEMBL176807 | C17H17N5O | 307.357 | 3 / 3 | 1.4 | Yes |
| 50869 |  CHEMBL307850 | C20H33ClN4 | 364.962 | 2 / 2 | 4.4 | Yes |
| 50894 |  CHEMBL1222864 | C30H40N6O3 | 532.689 | 6 / 0 | 1.6 | No |
| 50904 |  CHEMBL1774599 | C15H25N3O2 | 279.384 | 3 / 2 | 3.5 | Yes |
| 555669 |  CIPRALISANT | C14H20N2 | 216.328 | 1 / 1 | 3.3 | Yes |
| 52411 |  CHEMBL79709 | C16H26N4O | 290.411 | 3 / 2 | 1.6 | Yes |
| 52770 |  CID 44370617 | C14H21N3O6 | 327.337 | 7 / 4 | N/A | N/A |
| 52945 |  CHEMBL366977 | C18H16Cl2N4O | 375.253 | 2 / 3 | 3.8 | Yes |
| 52981 |  CHEMBL107123 | C20H23N3O2S | 369.483 | 4 / 2 | 3.3 | Yes |
| 53127 |  improgan | C9H14N6 | 206.253 | 3 / 3 | 0.1 | Yes |
| 53149 |  CHEMBL53056 | C12H15N3O2S | 265.331 | 4 / 2 | 1.0 | Yes |
| 53914 |  CHEMBL459542 | C28H40N2 | 404.642 | 2 / 0 | 6.7 | No |
| 54425 |  CHEMBL1223502 | C23H29ClN4O | 412.962 | 4 / 0 | 2.6 | Yes |
| 54811 |  CHEMBL274041 | C26H33N3O | 403.57 | 4 / 1 | 5.7 | No |
| 55724 |  CHEMBL313987 | C15H15N5OS | 313.379 | 4 / 3 | 1.6 | Yes |
| 55766 |  CHEMBL348656 | C27H33N5 | 427.596 | 3 / 3 | 4.8 | Yes |
| 55806 |  CID 44351978 | C17H18N2O6 | 346.339 | 7 / 3 | N/A | N/A |
| 55893 |  CHEMBL99540 | C22H31N5O2 | 397.523 | 4 / 3 | 4.6 | Yes |
| 56603 |  Iodoproxyfan | C13H15IN2O | 342.18 | 2 / 1 | 2.7 | Yes |
| 56705 |  CHEMBL2283089 | C24H46Cl3N3O | 499.002 | 4 / 4 | N/A | N/A |
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