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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Histamine H3 receptor
Species	Cavia porcellus (Guinea pig)
Gene	HRH3
Synonym	H3R HH3R
Disease	N/A for non-human GPCRs
Length	445
Amino acid sequence	MERAPPDGLMNASGALAGEAAAAAGGARTFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGVFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTSSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMVLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGAREAGPDPLPEAQSSPPQPPPGCWGCWPKGQGESMPLHRYGVGEAGPGAEAGEAALGGGSGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHSSLEHCWK
UniProt	Q9JI35
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5076
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL104300
Molecular formula	C20H30ClN3O2S
IUPAC name	1-(4-chlorophenyl)-N-[10-(1H-imidazol-5-yl)decyl]methanesulfonamide
Molecular weight	411.989
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	5.4
Synonyms	BDBM50217233 N-[10-(4-Imidazolyl)decyl](4-chlorophenyl)methanesulfonamide
Inchi Key	AGJNADSDYKCFNM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H30ClN3O2S/c21-19-12-10-18(11-13-19)16-27(25,26)24-14-8-6-4-2-1-3-5-7-9-20-15-22-17-23-20/h10-13,15,17,24H,1-9,14,16H2,(H,22,23)
PubChem CID	44335911
ChEMBL	CHEMBL104300
IUPHAR	N/A
BindingDB	50217233
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	58.88 nM	PMID10560733	ChEMBL
Ki	59.0 nM	PMID10560733	BindingDB
pKB	>5.0 -	PMID10560733	ChEMBL

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