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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1222865
Molecular formula	C29H40N6O2
IUPAC name	1-[3-(dimethylamino)propyl]-3-[1-[1-(pyridin-4-ylmethyl)piperidine-4-carbonyl]piperidin-4-yl]benzimidazol-2-one
Molecular weight	504.679
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	2.3
Synonyms	BDBM50325466 SCHEMBL8229223 1-(3-(dimethylamino)propyl)-3-(1-(1-(pyridin-4-ylmethyl)piperidine-4-carbonyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
Inchi Key	APPCPYUGJBDNJO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H40N6O2/c1-31(2)16-5-17-34-26-6-3-4-7-27(26)35(29(34)37)25-12-20-33(21-13-25)28(36)24-10-18-32(19-11-24)22-23-8-14-30-15-9-23/h3-4,6-9,14-15,24-25H,5,10-13,16-22H2,1-2H3
PubChem CID	49865043
ChEMBL	CHEMBL1222865
IUPHAR	N/A
BindingDB	50325466
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
11207	Histamine H3 receptor	Q9JI35	HRH3	Cavia porcellus (Guinea pig)	445

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