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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL366977
Molecular formula	C18H16Cl2N4O
IUPAC name	1-(3,5-dichlorophenyl)-3-[[4-(1H-imidazol-5-ylmethyl)phenyl]methyl]urea
Molecular weight	375.253
Hydrogen bond acceptor	2
Hydrogen bond donor	3
XlogP	3.8
Synonyms	BDBM86188 SCH 79687 D07KTP SCHEMBL7860131 224585-45-9 PDSP1_001301 SCH-79687 DTXSID20430941 PDSP2_001285 SCH79687 1-[4-(4-Imidazolylmethyl)benzyl]-3-(3,5-dichlorophenyl)urea L018853 [ Show all ]
Inchi Key	CXNCQFJNXQAFND-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H16Cl2N4O/c19-14-6-15(20)8-16(7-14)24-18(25)22-9-13-3-1-12(2-4-13)5-17-10-21-11-23-17/h1-4,6-8,10-11H,5,9H2,(H,21,23)(H2,22,24,25)
PubChem CID	9801743
ChEMBL	CHEMBL366977
IUPHAR	N/A
BindingDB	86188
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
52946	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
52943	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488
52944	Histamine H2 receptor	P47747	HRH2	Cavia porcellus (Guinea pig)	359
52945	Histamine H3 receptor	Q9JI35	HRH3	Cavia porcellus (Guinea pig)	445

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