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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Histamine H3 receptor
Species	Cavia porcellus (Guinea pig)
Gene	HRH3
Synonym	H3R HH3R
Disease	N/A for non-human GPCRs
Length	445
Amino acid sequence	MERAPPDGLMNASGALAGEAAAAAGGARTFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGVFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTSSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMVLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGAREAGPDPLPEAQSSPPQPPPGCWGCWPKGQGESMPLHRYGVGEAGPGAEAGEAALGGGSGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHSSLEHCWK
UniProt	Q9JI35
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5076
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL53412
Molecular formula	C23H31N3O2S
IUPAC name	N-[10-(1H-imidazol-5-yl)decyl]naphthalene-2-sulfonamide
Molecular weight	413.58
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	6.0
Synonyms	BDBM50216736 N-[10-(4-Imidazolyl)decyl]naphthalene-2-sulfonamide
Inchi Key	ANHJFDNMPMIHKX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H31N3O2S/c27-29(28,23-15-14-20-11-8-9-12-21(20)17-23)26-16-10-6-4-2-1-3-5-7-13-22-18-24-19-25-22/h8-9,11-12,14-15,17-19,26H,1-7,10,13,16H2,(H,24,25)
PubChem CID	44297197
ChEMBL	CHEMBL53412
IUPHAR	N/A
BindingDB	50216736
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	85.0 nM	PMID10406649	BindingDB
Ki	85.11 nM	PMID10406649	ChEMBL
Ki	138.0 nM	PMID10406649	BindingDB
Ki	138.04 nM	PMID10406649	ChEMBL
pKB	5.79 -	PMID10406649	ChEMBL

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