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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	GR-175737
Molecular formula	C14H13ClN4O
IUPAC name	3-[(4-chlorophenyl)methyl]-5-[2-(1H-imidazol-5-yl)ethyl]-1,2,4-oxadiazole
Molecular weight	288.735
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.2
Synonyms	176860-26-7 D0N2CN 3-[(4-chlorophenyl)methyl]-5-[2-(3H-imidazol-4-yl)ethyl]-1,2,4-oxadiazole GR175737 1,2,4-Oxadiazole, 3-((4-chlorophenyl)methyl)-5-(2-(1H-imidazol-4-yl)ethyl)- SCHEMBL195040 203874-78-6 GR 175737 GTPL1243 CHEMBL276798 3-(4-Chloro-benzyl)-5-[2-(1H-imidazol-4-yl)-ethyl]-[1,2,4]oxadiazole BDBM50070213 L015003 [ Show all ]
Inchi Key	CPOUJACQGWJJQB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H13ClN4O/c15-11-3-1-10(2-4-11)7-13-18-14(20-19-13)6-5-12-8-16-9-17-12/h1-4,8-9H,5-7H2,(H,16,17)
PubChem CID	9838905
ChEMBL	CHEMBL276798
IUPHAR	1243
BindingDB	50070213
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
47566	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488
47562	Histamine H2 receptor	P47747	HRH2	Cavia porcellus (Guinea pig)	359
47563	Histamine H3 receptor	Q9QYN8	Hrh3	Rattus norvegicus (Rat)	445
47565	Histamine H3 receptor	Q9JI35	HRH3	Cavia porcellus (Guinea pig)	445
553470	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445

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