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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	ciproxifan
Molecular formula	C16H18N2O2
IUPAC name	cyclopropyl-[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone
Molecular weight	270.332
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	2.5
Synonyms	HY-14567 NCGC00165775-01 SCHEMBL3335184 BCP04109 Ciproxifan; FUB 359 DTXSID50171532 LS-186999 PDSP1_001280 ZINC1892860 5EVQ7IRG99 CHEBI:125467 cyclopropyl-(4-(3-1H-imidazol-4-yl)propyloxyphenyl)ketone FT-0707540 FUB359 Methanone, cyclopropyl(4-(3-(1H-imidazol-5-yl)propoxy)phenyl)- SB19526 AKOS005266665 Cyclopropylpyrrol4-[3-(1H-imidazol-4-yl)propoxy] phenylmorphomethanone KB-76104 NCGC00165775-02 UNII-5EVQ7IRG99 4-[3-(4-cyclopropanecarbonylphenoxy)propyl]-1H-imidazole BDBM27213 CS-0664 EX-5964 LS-187638 PDSP2_001264 AC1O4Y0P cyclopropyl-[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone FUB 359 GTPL1265 MolPort-027-720-958 SC-26038 184025-18-1 AKOS030526676 Ciproxifan (FUB-359) D0I3XA L000187 NCGC00165775-03 Y0363 4CA-0550 BRD-K01767299-001-01-6 cyclopropyl 4-(3-(1H-imidazol-4-yl)propyloxy)phenyl ketone EX-A077 FUB-359 Methanone, cyclopropyl(4-(3-(1H-imidazol-4-yl)propoxy)phenyl)- S-7718 (4-(3-(1H-imidazol-4-yl)propoxy)phenyl)(cyclopropyl)methanone ACQBHJXEAYTHCY-UHFFFAOYSA-N CHEMBL14638 cyclopropyl-[4-[3-(3H-imidazol-4-yl)propoxy]phenyl]methanone [ Show all ]
Inchi Key	ACQBHJXEAYTHCY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H18N2O2/c19-16(12-3-4-12)13-5-7-15(8-6-13)20-9-1-2-14-10-17-11-18-14/h5-8,10-12H,1-4,9H2,(H,17,18)
PubChem CID	6422124
ChEMBL	CHEMBL14638
IUPHAR	1265
BindingDB	27213
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1782	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
1784	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462
1783	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
1788	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
1789	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
1781	Histamine H3 receptor	Q9JI35	HRH3	Cavia porcellus (Guinea pig)	445
1785	Histamine H3 receptor	Q9QYN8	Hrh3	Rattus norvegicus (Rat)	445
1786	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
1790	Histamine H3 receptor	P58406	Hrh3	Mus musculus (Mouse)	445
1787	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390

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